2020
DOI: 10.31219/osf.io/v7jw3
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Murat Seyran, Damiano Pizzol, Parise Adadi et al.

Abstract: There is a consensus that SARS-CoV-2 originated naturally from BatCoVs. Although based on phylogenetic analysis SARS-CoV-2 seems to be related to BatCoVs RaTG13 or RmYN02, its exact origin of lineage is not clear. In fact, the flat and non-sunken surface of the sialic acid-binding domain of SARS-CoV-2 spike protein conflicts with the general adaptation and survival pattern observed for all other coronaviruses (CoVs). Unlike RaTG13, for SARS-CoV-2 a recombination apparently occured between the S1/S2 domains of …

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