Unipolar Anodal Electrolytic Lesions in the Brain of Man and Cat

Ablation Modalities for Therapeutic Intervention in Arrhythmia-Related Cardiovascular Disease: Focus on Electroporation

“…Temperatures of ≥50 °C induce tissue necrosis; however, temperatures approaching 100 °C can cause a coagulum of denatured proteins and plasma to form on the catheter tip, impeding current delivery [ 20 ] ( Figure 2 ). RF-induced lesions typically have well-defined borders and their shape can adopt a monopolar egg shape or a bipolar round-brick shape [ 25 , 26 ]. RF lesion shape is dependent on a number of factors including catheter tip diameter, inter-tip spacing, tissue contact, temperature and duration of energy pulse delivered [ 25 , 26 , 27 ].…”

“…RF-induced lesions typically have well-defined borders and their shape can adopt a monopolar egg shape or a bipolar round-brick shape [ 25 , 26 ]. RF lesion shape is dependent on a number of factors including catheter tip diameter, inter-tip spacing, tissue contact, temperature and duration of energy pulse delivered [ 25 , 26 , 27 ]. RF is a clinically significant technique as an ablation treatment for atrial fibrillation (AF), with success rates generally ranging anywhere between 45% and 80% [ 4 , 28 , 29 ].…”

Ablation Modalities for Therapeutic Intervention in Arrhythmia-Related Cardiovascular Disease: Focus on Electroporation

“…Temperatures of ≥50 °C induce tissue necrosis; however, temperatures approaching 100 °C can cause a coagulum of denatured proteins and plasma to form on the catheter tip, impeding current delivery [ 20 ] ( Figure 2 ). RF-induced lesions typically have well-defined borders and their shape can adopt a monopolar egg shape or a bipolar round-brick shape [ 25 , 26 ]. RF lesion shape is dependent on a number of factors including catheter tip diameter, inter-tip spacing, tissue contact, temperature and duration of energy pulse delivered [ 25 , 26 , 27 ].…”

“…RF-induced lesions typically have well-defined borders and their shape can adopt a monopolar egg shape or a bipolar round-brick shape [ 25 , 26 ]. RF lesion shape is dependent on a number of factors including catheter tip diameter, inter-tip spacing, tissue contact, temperature and duration of energy pulse delivered [ 25 , 26 , 27 ]. RF is a clinically significant technique as an ablation treatment for atrial fibrillation (AF), with success rates generally ranging anywhere between 45% and 80% [ 4 , 28 , 29 ].…”

Radiofrequency Lesioning for Movement and Psychiatric Disorders-Experience of 107 Cases

“…Radiofrequency lesioning (RFL) was introduced in 1953 when William Sweet showed that radiofrequency (RF) lesioning could provide a more precise and quantifiable lesion over direct current lesioning, which was being practiced during that period ( Sweet and Mark, 1953 ). Over the subsequent years, with the progressive development in the technology of RF lesioning, stereotactic apparatus, CT and MRI scans, coupled with the knowledge and understanding of psychiatric and movement disorders, there was widespread utilization of lesioning in functional neurosurgery ( Lozano et al, 2018 ).…”

The medial preoptic area modulates cocaine-induced activity in female rats.

“…Ablations produced with radiofrequency lesion generators are more reproducible in size and shape than are those produced with electrolytic or chemical techniques. For example, electrolytic lesions can vary up to a factor of 4 in terms of size and geometry, after fixed lesion current and time were applied (Sweet & Mark, 1953). The reason for this variability is that electrolytic lesions are influenced by electrolysis action, gas formation, anatomy of tissue planes, and nearby vascular interruption, which can vary between animals.…”

Ablation Modalities for Therapeutic Intervention in Arrhythmia-Related Cardiovascular Disease: Focus on Electroporation

“…Temperatures of ≥50 °C induce tissue necrosis; however, temperatures approaching 100 °C can cause a coagulum of denatured proteins and plasma to form on the catheter tip, impeding current delivery [ 20 ] ( Figure 2 ). RF-induced lesions typically have well-defined borders and their shape can adopt a monopolar egg shape or a bipolar round-brick shape [ 25 , 26 ]. RF lesion shape is dependent on a number of factors including catheter tip diameter, inter-tip spacing, tissue contact, temperature and duration of energy pulse delivered [ 25 , 26 , 27 ].…”

“…RF-induced lesions typically have well-defined borders and their shape can adopt a monopolar egg shape or a bipolar round-brick shape [ 25 , 26 ]. RF lesion shape is dependent on a number of factors including catheter tip diameter, inter-tip spacing, tissue contact, temperature and duration of energy pulse delivered [ 25 , 26 , 27 ]. RF is a clinically significant technique as an ablation treatment for atrial fibrillation (AF), with success rates generally ranging anywhere between 45% and 80% [ 4 , 28 , 29 ].…”

Radiofrequency Lesioning for Movement and Psychiatric Disorders-Experience of 107 Cases

“…Radiofrequency lesioning (RFL) was introduced in 1953 when William Sweet showed that radiofrequency (RF) lesioning could provide a more precise and quantifiable lesion over direct current lesioning, which was being practiced during that period ( Sweet and Mark, 1953 ). Over the subsequent years, with the progressive development in the technology of RF lesioning, stereotactic apparatus, CT and MRI scans, coupled with the knowledge and understanding of psychiatric and movement disorders, there was widespread utilization of lesioning in functional neurosurgery ( Lozano et al, 2018 ).…”

The medial preoptic area modulates cocaine-induced activity in female rats.

“…Ablations produced with radiofrequency lesion generators are more reproducible in size and shape than are those produced with electrolytic or chemical techniques. For example, electrolytic lesions can vary up to a factor of 4 in terms of size and geometry, after fixed lesion current and time were applied (Sweet & Mark, 1953). The reason for this variability is that electrolytic lesions are influenced by electrolysis action, gas formation, anatomy of tissue planes, and nearby vascular interruption, which can vary between animals.…”

Ablation Modalities for Therapeutic Intervention in Arrhythmia-Related Cardiovascular Disease: Focus on Electroporation

“…Temperatures of ≥50 °C induce tissue necrosis; however, temperatures approaching 100 °C can cause a coagulum of denatured proteins and plasma to form on the catheter tip, impeding current delivery [ 20 ] ( Figure 2 ). RF-induced lesions typically have well-defined borders and their shape can adopt a monopolar egg shape or a bipolar round-brick shape [ 25 , 26 ]. RF lesion shape is dependent on a number of factors including catheter tip diameter, inter-tip spacing, tissue contact, temperature and duration of energy pulse delivered [ 25 , 26 , 27 ].…”

“…RF-induced lesions typically have well-defined borders and their shape can adopt a monopolar egg shape or a bipolar round-brick shape [ 25 , 26 ]. RF lesion shape is dependent on a number of factors including catheter tip diameter, inter-tip spacing, tissue contact, temperature and duration of energy pulse delivered [ 25 , 26 , 27 ]. RF is a clinically significant technique as an ablation treatment for atrial fibrillation (AF), with success rates generally ranging anywhere between 45% and 80% [ 4 , 28 , 29 ].…”

Radiofrequency Lesioning for Movement and Psychiatric Disorders-Experience of 107 Cases

“…Radiofrequency lesioning (RFL) was introduced in 1953 when William Sweet showed that radiofrequency (RF) lesioning could provide a more precise and quantifiable lesion over direct current lesioning, which was being practiced during that period ( Sweet and Mark, 1953 ). Over the subsequent years, with the progressive development in the technology of RF lesioning, stereotactic apparatus, CT and MRI scans, coupled with the knowledge and understanding of psychiatric and movement disorders, there was widespread utilization of lesioning in functional neurosurgery ( Lozano et al, 2018 ).…”

The medial preoptic area modulates cocaine-induced activity in female rats.

“…Ablations produced with radiofrequency lesion generators are more reproducible in size and shape than are those produced with electrolytic or chemical techniques. For example, electrolytic lesions can vary up to a factor of 4 in terms of size and geometry, after fixed lesion current and time were applied (Sweet & Mark, 1953). The reason for this variability is that electrolytic lesions are influenced by electrolysis action, gas formation, anatomy of tissue planes, and nearby vascular interruption, which can vary between animals.…”