Unilateral segmental hyperhidrosis. Response to 20% aluminum chloride solution and plastic wrap

Abstract

A young woman had unilateral dermatomal hyperhidrosis documented by a starch-iodine technique. Evaluation failed to reveal any associated causative conditions. She was treated with 20% aluminum chloride hexahydrate solution in absolute alcohol (Drysol) with a favorable response. With recurrent use, however, she developed miliaria following exertion. Aluminum chloride hexahydrate was shown to be an effective agent to treat this unusual condition, but miliaria with exertion secondary to its use may be a limiting factor.

Idiopathic Localized Unilateral Hyperhidrosis in a Child

“…No associated neurologic, vascular, or endocrinologic findings are detected (2,3). A summary of reported cases is included in Table 1(10–25). Including our patient, approximately 30 patients who meet the definition of idiopathic unilateral localized hyperhidrosis have been documented in the literature.…”

“…Several cutaneous diseases have been described in association with localized hyperhidrosis, including palmoplantar keratodermas (1), glomus tumors (6), blue rubber bleb nevus (7), POEMS syndrome (8), and pachydermoperiostosis (9). Lastly, several cases have been described without an apparent associated cause (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25). This latter condition has been termed idiopathic localized unilateral hyperhidrosis.…”