Undifferentiated Carcinoma of Nasopharyngeal Type of Tonsil

Non‐nasopharyngeal head and neck lymphoepithelioma‐like carcinoma in the United States: A population‐based study

“…In this study, most patients were men, with a male:female ratio of 1.8:1, similar to other studies examining non‐nasopharyngeal head and neck LELC . The majority of the cases in this study ( n = 130) were located in the oropharynx, of which 112 occurred in the white population, comparable to other case series originating from the United States and Europe . The second most common site of LELC was the salivary glands with cases that have been mainly reported in Greenland Eskimo's, North American Eskimo's, and the Chinese population .…”

“…13,16,17 The majority of the cases in this study (n 5 130) were located in the oropharynx, of which 112 occurred in the white population, comparable to other case series originating from the United States and Europe. 16,18,19 The second most common site of LELC was the salivary glands with cases that have been mainly reported in Greenland Eskimo's, North American Eskimo's, and the Chinese population. 10,13,20,21 Of the 113 cases occurring in the salivary glands in this study, 66 (58.4%) were in the white population, whereas within the non-white population, 44 cases (38.9%) occurred in patients of another race.…”

Lymphoepithelioma-Like Carcinoma of the Skin: A Report of Two Cases Treated With Complete Microscopic Margin Control and Review of Literature

“…LELCS histologically resembles the lymphoepitheliomatous malignancies that have been described to occur in the nasopharynx, 4 palatine tonsils, 5 salivary glands, 6 lung, 7–9 thymus, 10 gastrointestinal tract, 11,12 kidney, 13,14 ureter, 15,16 urinary bladder, 17 breast, 18 and uterine cervix 19 . Microscopic examination reveals a multifocal distribution of tumor involving the mid to reticular dermis and occasionally the subcutis and skeletal muscle 1,20 .…”

Lymphoepithelial Carcinoma: Two Case Reports and a Systematic Review of Oral and Sinonasal Cases

“…The sensitivity of the methods for testing EBV in various publications has varied. Either highly sensitive ISH, clearly less sensitive IHC, or rather unspecific EBV serology (indicating only the general EBV infection) have been used across different studies [10,30,33]. It has been suggested that IHC for determining EVB infection is actually unnecessary because of it is irrelevant information for therapeutic or prognostic purposes [11,20,39].…”