Understanding the future research needs in Postural Orthostatic Tachycardia Syndrome (POTS): Evidence mapping the POTS adult literature

The value of dynamic elastomeric fabric orthoses in the management of a complex hypermobile Ehlers‐Danlos syndrome patient: A case report

“…Postural Tachycardia Syndrome, a comorbidity found in EDS, 21 is defined as a clinical syndrome lasting at least 6 months that is characterized by: (1) an increase in heart rate ≥30 beats per minute within 5–10 min of quiet standing or upright tilt (or ≥40 beats per minute in individuals 12–19 years of age); (2) the absence of orthostatic hypotension (>20 mm Hg drop in systolic blood pressure); and (3) frequent symptoms that occur with standing such as lightheadedness, palpitations, tremulousness, generalized weakness, blurred vision, exercise intolerance, and fatigue 22 . Compression garments have been highlighted as a tool in the management of PoTS, 23,24 therefore the compressive effects of DEFOs might help to reduce symptoms. The management of hEDS must focus on treatment interventions that allow these patients to function, addressing “injury prevention and symptom amelioration rather than a cure” 25 …”

Co-creation of a complex, multicomponent rehabilitation intervention and feasibility trial protocol for the PostUraL tachycardia Syndrome Exercise (PULSE) study

“…There are no multicentre randomised control trials (RCT) testing exercise rehabilitation for people living with PoTS, and no studies employing intervention or research protocol co-development methodology. There is a lack of good quality evidence including people across the PoTS spectrum (15). As a consequence, exercise rehabilitation programmes for people living with PoTS are not commissioned in the United Kingdom (UK).…”

The value of Dynamic Movement Orthoses in the management of a complex Hypermobile Ehlers-Danlos Syndrome patient: a case report

“…]40 beats per minute in individuals 12 to 19 years of age); 2) the absence of orthostatic hypotension (>20 mm Hg drop in systolic blood pressure); and 3) frequent symptoms that occur with standing such as light headedness, palpitations, tremulousness, generalized weakness, blurred vision, exercise intolerance, and fatigue [22]. Compression garments have been highlighted as a tool in the management of PoTS [23,24], therefore the compressive effects of DMOs(r) might help to reduce symptoms. The management of hEDS must focus on treatment interventions that allow these patients to function, addressing "injury prevention and symptom amelioration rather than a cure" [25].…”