2019
DOI: 10.1038/s41585-019-0148-8
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Abstract: An estimated 4–5 million CT scans are performed in the USA every year to investigate nephrourological diseases such as urinary stones and renal masses. Despite the clinical benefits of CT imaging, concerns remain regarding the potential risks associated with exposure to ionizing radiation. To assess the potential risk of harmful biological effects from exposure to ionizing radiation, understanding the mechanisms by which radiation damage and repair occur is essential. Although radiation level and cancer risk f… Show more

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Cited by 24 publications
(102 citation statements)
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References 84 publications
(102 reference statements)
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“…As the use of CT in modern medicine continues to increase, people are beginning to pay attention to increasing the radiation dose from biomedical imaging to the community and the associated increase in the estimated risk of radiation-induced cancer [38]. The optimization of the scanning method is important, so the necessary clinical information can be collected or captured while minimizing the radiation dose [39]. The proposed general workflow for biomedical image denoising is presented in Figure 1.…”
Section: Methodsmentioning
confidence: 99%
“…As the use of CT in modern medicine continues to increase, people are beginning to pay attention to increasing the radiation dose from biomedical imaging to the community and the associated increase in the estimated risk of radiation-induced cancer [38]. The optimization of the scanning method is important, so the necessary clinical information can be collected or captured while minimizing the radiation dose [39]. The proposed general workflow for biomedical image denoising is presented in Figure 1.…”
Section: Methodsmentioning
confidence: 99%
“…Computed tomography (CT) has become a key diagnostic imaging modality in clinical diagnosis of a wide range of diseases. The number of CT scans in the US had an average annual increase of 10% between 1995 and 2015 (IMV Publising 2018, Ferrero et al 2019. The sharp utilization trend of CT imaging in clinical setting has raised health concerns regarding potential risks of ionizing radiation on patients undergoing CT examinations.…”
Section: Introductionmentioning
confidence: 99%
“…Ultrasound and computerised tomography (CT) provide good anatomic details but limited functional evaluation. CT additionally requires the use of iodinated contrast material and exposure to ionising radiation, which is injurious to the kidney 7 . Nuclear medicine assessments provide functional information but lack spatial resolution 8 .…”
Section: Introductionmentioning
confidence: 99%
“…CT additionally requires the use of iodinated contrast material and exposure to ionising radiation, which is injurious to the kidney. 7 Nuclear medicine assessments provide functional information but lack spatial resolution. 8 Magnetic resonance imaging (MRI) is the unique modality to provide both structural and functional information.…”
mentioning
confidence: 99%