volume 9, issue 1, P60-69 2016
DOI: 10.15283/ijsc.2016.9.1.60
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Abstract: Background and ObjectivesType 1 Diabetes Mellitus (T1DM) is an autoimmune disorder resulting out of T cell mediated destruction of pancreatic beta cells. Immunomodulatory properties of mesenchymal stem cells may help to regenerate beta cells and/or prevent further destruction of remnant, unaffected beta cells in diabetes. We have assessed the ability of umbilical cord derived MSCs (UCMSCs) to differentiate into functional islet cells in vitro.Methods and ResultsWe have isolated UCMSCs and allowed sequential ex…

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