Ultraviolet Radiation of Melanocytic Nevi

Effect of narrowband ultraviolet B phototherapy on melanocytic naevi

“…Around half of naevi exposed to a course of NB‐UVB underwent size or morphological changes. Overall the morphological changes observed in this cohort were in concordance with previous studies 2,4 …”

Clinically equivocal melanocytic skin lesions with features of regression: a dermoscopic-pathological study

“…In the present study, most of the lesions with BWS were located on the back. This is consistent with previous reports assessing the morphological changes of dermoscopic structures in ultraviolet (UV)‐irradiated or sun‐exposed naevi 27–29 . It might be speculated that intermittent sun exposure could effect regression in melanocytic naevi.…”

Clinical Characteristics in Early Childhood Associated with a Nevus-Prone Phenotype in Adults from Tropical Australia: Two Decades of Follow-Up of the Townsville Preschool Cohort Study

“…Childhood is a period of susceptibility to the long-term harmful effects of sun-exposure [7], as evidenced by differences in melanoma-risk between child and adult migrants moving from high to lower latitudes [3,7]. Our results support the hypothesis that early sunburn influences the proliferation of melanocytic nevi, increasing melanoma-risk in sun-sensitive individuals [3,4], and are consistent with earlier findings from our entire cohort [5,6,8]; those of the SONIC childhood nevus cohort in the USA [7,26]; and the transient dermoscopic changes observed in UV-irradiated nevi [31], as well as a pooled-analysis of 5700 cases and 7216 controls (drawn from 13 studies) demonstrating that childhood sunburn increases melanoma-risk for the trunk and limbs by 50% and the head and neck by 40% [32]. However, lifetime number of painful sunburns experienced in the first three decades was not significantly related to the number of incident nevi of all sizes (p = 0.079) or ≥2 mm (p = 0.329) in our study, even though the trend was indicative of a dose-response.…”