Ultrasound Thermal Effect Enriched by Adding of Micro and Nano Particles to the Agar-Gel Tissue Mimicking Materials

Kruglenko, Eleonora; Korczak, Ilona; Litniewski, Jerzy; Gambin, Barbara

doi:10.1109/acoustics.2018.8502361

Cited by 5 publications

(7 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A cylindroid agar phantom with glass beads of 75 ± 5 µm in diameter (Supelco 59200-U) was fabricated as a soft-tissue-mimicking material by referring to recipes in the literature. 20,21) It is expected that the agar phantom has 32 scatterers per cubic millimeter. At the same time, pork Boston Butt was prepared as a soft tissue specimen.…”

Section: Methodsmentioning

confidence: 99%

Measurement of internal temperature in biological tissue specimen with deformation by statistical analysis of ultrasonic scattered echoes

Takeuchi

Matsui

Doi

et al. 2018

Jpn. J. Appl. Phys.

View full text Add to dashboard Cite

In this paper, we present the Nakagami shape parameter m estimated by the statistical analysis of ultrasonic scattered echoes from a soft-tissue-mimicking phantom and a soft tissue heated from room temperature up to 42.0 °C. The ratio change of m values for both phantom and biological tissue specimens clearly show temperature dependence. We show changes in the internal temperature of the biological tissue specimens using two-dimensional hot-scale images indicating absolute values of the ratio change of m values. However, in an in vitro experiment using porcine tissue, no clear change of m values was observed with a smaller region of interest (ROI) owing to the tissue deformation during heating. We could obtain the temperature-dependent ratio change of m values by increasing the ROI size. These results suggest that the selection of a proper ROI size would be significantly important for detecting internal temperature changes by the ratio change of m values because not only the tissue deformation owing to heating but also body motion and pulsating exist under in vivo conditions.

show abstract

Section: Methodsmentioning

confidence: 99%

Measurement of internal temperature in biological tissue specimen with deformation by statistical analysis of ultrasonic scattered echoes

Takeuchi

Matsui

Doi

et al. 2018

Jpn. J. Appl. Phys.

View full text Add to dashboard Cite

show abstract

“…In what follows we use abbreviated names for these two samples with nanoparticles, MNP8 and MNP16, depending on particle fraction, respectively, cf. [26,28]. In Fig.…”

Section: Methodsmentioning

confidence: 97%

“…TMM agar-based samples. Procedures of samples preparation together with materials used in them, also thermal heating experiments performed were analogous to these was described in detail in [26], and [28]. The dedicated hyperthermia experimental setup described in these papers was specially designed with thermocouple guides to locate them precisely on the beam axis, cf.…”

Section: Methodsmentioning

confidence: 99%

Bulletin of the Polish Academy of Sciences: Technical Sciences

Gambin,

Kruglenko

2021

View full text Add to dashboard Cite

Magnetic nanoparticle's different applications in nanomedicine, due to their unique physical properties and biocompatibility, were intensively investigated. Recently, Fe 3 O 4 nanoparticles, are confirmed to be the best sonosensitizers to enhance the performance of HIFU (high intensity focused ultrasound). They are also used as thermo-sensitizers in magnetic hyperthermia. A new idea of dual, magneto-ultrasound, coupled hyperthermia allows the ultrasound intensity to be reduced from the high to a moderate level. Our goal is to evaluate the enhancement of thermal effects of focused ultrasound of moderate intensity due to the presence of nanoparticles. We combine experimental results with numerical analysis. Experiments are performed on tissue-mimicking materials made of the 5% agar gel and gel samples containing Fe 3 O 4 nanoparticles with φ = 100 nm with two fractions of 0.76 and 1.53% w/w. Thermocouples registered curves of temperature rising during heating by focused ultrasound transducer with acoustic powers of the range from 1 to 4 W. The theoretical model of ultrasound-thermal coupling is solved in COMSOL Multiphysics. We compared the changes between the specific absorption rates (SAR) coefficients determined from the experimental and numerical temperature rise curves depending on the nanoparticle fractions and applied acoustic powers.We confirmed that the significant role of nanoparticles in enhancing the thermal effect is qualitatively similarly estimated, based on experimental and numerical results. So that we demonstrated the usefulness of the FEM linear acoustic model in the planning of efficiency of nanoparticle-mediated moderate hyperthermia.

show abstract

“…Therefore, it is necessary to develop new additives to improve the performance of polymer gel. In recent years, graphite materials have attracted much attention as a hot topic in the field of micro-materials [25][26][27][28][29]. The modified hydrophilic micron graphite powder has a layered structure with abundant hydroxyl and carboxyl functional groups on its surface, so it can be uniformly dispersed in water.…”

Section: Introductionmentioning

confidence: 99%

Study on a Strong Polymer Gel by the Addition of Micron Graphite Oxide Powder and Its Plugging of Fracture

Shi,

Zhang,

Zhang

et al. 2024

Gels

View full text Add to dashboard Cite

It is difficult to plug the fracture water channeling of a fractured low-permeability reservoir during water flooding by using the conventional acrylamide polymer gel due to its weak mechanical properties. For this problem, micron graphite powder is added to enhance the comprehensive properties of the acrylamide polymer gel, which can improve the plugging effect of fracture water channeling. The chemical principle of this process is that the hydroxyl and carboxyl groups of the layered micron graphite powder can undergo physicochemical interactions with the amide groups of the polyacrylamide molecule chain. As a rigid structure, the graphite powder can support the flexible skeleton of the original polyacrylamide molecule chain. Through the synergy of the rigid and flexible structures, the viscoelasticity, thermal stability, tensile performance, and plugging ability of the new-type gel can be significantly enhanced. Compared with a single acrylamide gel, after adding 3000 mg/L of micrometer-sized graphite powder, the elastic modulus, the viscous modulus, the phase transition temperature, the breakthrough pressure gradient, the elongation at break, and the tensile stress of the acrylamide gel are all greatly improved. After adding the graphite powder to the polyacrylamide gel, the fracture water channeling can be effectively plugged. The characteristics of the networked water flow channel are obvious during the injected water break through the gel in the fracture. The breakthrough pressure of water flooding is high. The experimental results are an attempt to develop a new gel material for the water plugging of a fractured low-permeability reservoir.

show abstract

Ultrasound Thermal Effect Enriched by Adding of Micro and Nano Particles to the Agar-Gel Tissue Mimicking Materials

Cited by 5 publications

References 11 publications

Measurement of internal temperature in biological tissue specimen with deformation by statistical analysis of ultrasonic scattered echoes

Measurement of internal temperature in biological tissue specimen with deformation by statistical analysis of ultrasonic scattered echoes

Bulletin of the Polish Academy of Sciences: Technical Sciences

Study on a Strong Polymer Gel by the Addition of Micron Graphite Oxide Powder and Its Plugging of Fracture

Contact Info

Product

Resources

About