Ultrasound-guided embryo transfer improves pregnancy rates and increases the frequency of easy transfers

Self Cite

Purpose The aim of our study was to ascertain the influence of hCG levels at oocyte pick-up on IVF outcomes, and their relationship with clinical parameters. Methods A prospective study was performed including 473 women undergoing IVF, aged under 40 years. Blood samples to analyze hCG levels were obtained at the time of follicular aspiration, 36 h after the administration of 250 μg of recombinant hCG.Results Neither the numbers of oocytes obtained or fertilized, nor the pregnancy rate, were correlated with hCG levels. Moreover, hCG values were very similar in women who did and did not become pregnant (123.3±48.7 and 117.5±44.7 mUI/mL). Cases in which no oocytes were recovered after follicular aspiration had similar hCG levels to those in which more than 1 oocyte was obtained. On the other hand, hCG levels were negatively related to body mass index, weight, and age. Conclusions These data indicate that after the administration of 250 μg of recombinant hCG, hCG levels are not responsible for failure to recover oocytes. Specifically, there was no correlation between plasma hCG levels and the number of oocytes obtained or other markers of IVF outcome. There was, however, an inverse relationship with BMI, body weight and age.

Section: Methodsmentioning

confidence: 99%

Human chorionic gonadotropin (hCG) plasma levels at oocyte retrieval and IVF outcomes

Matorras

Meabe

Mendoza

et al. 2012

Self Cite

“…The embryo transfer can be performed in three ways: (1) blind (clinical touch); (2) based on information on the length of the uterus (obtained by previous ultrasonographic measurement or mock transfer); (3) guided by abdominal ultrasonography. It is advantageous to place the embryos into the uterus in as atraumatic a manner as possible [1][2][3]. Uterine contractions [4,5], presence of blood on the catheter [6,7], bacterial contamination of the catheter [8], difficulty of transfer [9], and the type of catheter [10][11][12][13], all influence the success rate of the IVF/ICSI treatment.…”

Section: Introductionmentioning

confidence: 99%

The impact of the depth of embryo replacement on IVF outcome

Pacchiarotti

Mohamed

Micara

et al. 2007

Purpose: To evaluate the effect of the depth of embryo transfer replacement on clinical pregnancy rate.Methods: Data from a total of 104 consecutive embryo transfers performed on 104 womenn aged 26-37 years were prospectively collected for this study. All patients underwent a standard down regulation protocol for ovarian stimulation. Oocytes retrieval were performed at 36 h after hCG administration. Embryo transfer took place at 48 h after insemination. The patients were matched in two groups according to the distance between the tip of the catheter and the uterine fundus at transfer (group A > 10 < 15 mm and group B ≤ 10 mm). The same method of loading embryos into the embryo transfer catheter was used.Results: Clinical pregnancy rates varied significantly (p ≤ 0.05) between the two groups: 27.7% in group A and 14% in group B. The number and quality of embryos transferred did not differ between the groups.Conclusions: The results suggest that the depth of embryo replacement may be an important variable in embryo transfer technique.

“…Recently, ultrasound-guided embryo transfer has been reported to improve the clinical pregnancy rate after IVF. For example, the clinical pregnancy rate among those undergoing embryo transfer with ultrasound guidance has been reported in the range of 38.4-50%, considerably higher than the 25.4-33.7%, reported for those embryo transfer was not assisted by ultrasound (4)(5)(6)(7)(8). Conversely, one study did not show any statistical difference in the pregnancy rate between the ultrasound-guided group (26.0%) and the nonultrasound-guided group (22.5%) (9).…”

Section: Introductionmentioning

confidence: 90%

Abdominal Ultrasound-Guided Embryo Transfer Improves Clinical Pregnancy Rates After In Vitro Fertilization: Experiences from 330 Clinical Investigations

Lü

Hao

et al. 2005

Purpose : To investigate the effect of ultrasound-guided embryo transfer on the rate of implantation and clinical pregnancy. Methods : A prospective randomized trial was performed to compare ultrasound-guided embryo transfer with the traditional method. A total of 330 patients were randomly divided into two groups on the day of embryo transfer. For the cases (n = 178), ultrasound-guided was used; controls (n = 152) was performed using routine methods. Results : The rate of implantation and clinical pregnancy for the cases (19.6 and 37.1%, respectively) was significantly higher than for the controls (12.6 and 25%, respectively; p < 0.05). Conclusion : Ultrasound-guided embryo transfer can significantly increase the rate of implantation and clinical pregnancy, and should be recommended as a routine procedure in the process of in vitro fertilization and embryo transfer (IVF-ET).