Ultrasound Elastography: Principles, Techniques, and Clinical Applications

DeWall, Ryan J.

doi:10.1615/critrevbiomedeng.2013006991

Cited by 91 publications

(75 citation statements)

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“…Method Dynamic elastography is based on the assessment of the propagation of shear waves within tissues to calculate the visco-elastic properties [18]. Displacements can be measured with ultrasonography or MR imaging and stress can be applied either externally or internally.…”

Section: Dynamic Ultrasound Elastographymentioning

confidence: 99%

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New imaging techniques for liver diseases

Beers

Daire

Garteiser

2015

Journal of Hepatology

109

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Newly developed or advanced methods of ultrasonography and MR imaging provide combined anatomical and quantitative functional information about diffuse and focal liver diseases. Ultrasound elastography has a central role for staging liver fibrosis and an increasing role in grading portal hypertension; dynamic contrast-enhanced ultrasonography may improve tumor characterization. In clinical practice, MR imaging examinations currently include diffusion-weighted and dynamic MR imaging, enhanced with extracellular or hepatobiliary contrast agents. Moreover, quantitative parameters obtained with diffusion-weighted MR imaging, dynamic contrast-enhanced MR imaging and MR elastography have the potential to characterize further diffuse and focal liver diseases, by adding information about tissue cellularity, perfusion, hepatocyte transport function and visco-elasticity. The multiparametric capability of ultrasonography and more markedly of MR imaging gives the opportunity for high diagnostic performance by combining imaging biomarkers. However, image acquisition and post-processing methods should be further standardized and validated in multicenter trials.

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Section: Dynamic Ultrasound Elastographymentioning

confidence: 99%

“…The latter case includes methods that apply a force internally, for example by using focused ultrasound pulses generating acoustic radiation force (ARF). Acoustic pulses are used to ''push'' tissue, as well as capture the resulting tissue motion [18].…”

Section: Dynamic Ultrasound Elastographymentioning

confidence: 99%

New imaging techniques for liver diseases

Beers

Daire

Garteiser

2015

Journal of Hepatology

109

View full text Add to dashboard Cite

show abstract

“…The basic principle of elastography is to generate a stress in a tissue and then to measure the strain induced by this stress [5]. The tissue stiffness is quantified with Young modulus, defined by the ratio between the applied stress and the induced strain and expressed in pressure units -Pascals or kilo Pascals [6,7].…”

Section: Ultrasound Elastography Techniquesmentioning

confidence: 99%

Value of ultrasound elastography in the diagnosis of native kidney fibrosis.

et al. 2016

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In the last decade ultrasound elastography, an already widely used technique in the diagnosis of hepatic fibrosis, has raised the attention of nephrologists as a potential valuable noninvasive tool for the diagnosis of renal fibrosis. Due to renal deep location and anatomic complexity, the shear wave techniques are the most appropriate elastography methods for exploring native kidneys. Recent research offers promising results, but further larger studies are required for a better standardization of this method and also for establishing reference values of normal kidney elasticity. This article reviews the studies conducted for exploring the native kidney, highlighting the advantages and limitations of ultrasound elastography for assessing fibrosis development in chronic kidney diseases.

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“…Ultrasonography (US) is noninvasive and can give useful clues in the diagnosis of cervical lymphadenopathy, however, the differential diagnosis is difficult in some situations even combined with color Doppler imaging (Khanna et al, 2011). Real time elastography (RTE) is a newly developing technique that can reflect the stiffness of organs and has very good results in differentiating tumors of the breast, thyroid, prostate, pancreas and lymph nodes (Dewall, 2013). For lymph nodes evaluation, most research focused on the differentiation of benign and malignant superficial lymph nodes, and malignant lymph nodes usually refer to metastasis (Ying et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Clinical Value of Real Time Elastography in Patients with Unexplained Cervical Lymphadenopathy: Quantitative Evaluation

Fu¹,

Yun-fei²,

Yan³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Ultrasonography is non-invasive and can give useful clues in the diagnosis of cervical lymphadenopathy, However, differential diagnosis is difficult in some situations even combined with color Doppler imaging. The present study was conducted to evaluate the clinical value of real time elastography in patients with unexplained cervical lymphadenopathy using a quantitative method. From May 2011 to February 2012, 39 enlarged lymph nodes from 39 patients with unexplained cervical lymphadenopathy were assessed. All the patients were examined by both B-mode ultrasound, color Doppler flow imaging and elastography. The method of analyzing elasto-graphic data was the calculation of the 10 parametres ("mean", "sd", "area%", "com", "kur", "ske", "con", "ent", "idm", "asm") offered by the software integrated into the Hitachi system. The findings were then correlated with the definitive tissue diagnosis obtained by lymph node dissection or biopsy. Final histology revealed 10 cases of metastatic lymph nodes, 11 cases of lymphoma, 12 cases of tuberculosis and 6 cases of nonspecific lymphadenitis. The significant distinguishing features for conventional ultrasound were the maximum short diameter (p=0.007) and absent of echogenic hilum (p=0.0293). The diagnostic accuracy was 43.6% (17/39 cases) and there were 17 patients with equivocal diagnosis. For elastography, "mean" (p=0.003), "area%" (p=0.009), "kurt" (p=0.0291), "skew" (p=0.014) and "cont" (p=0.012) demonstrated significant differences between groups. With 9 of the 17 patients with previous equivocal diagnoses (52.9%) definite and correct diagnoses could be obtained. The diagnostic accuracy for conventional ultrasound combined elastography was 69.2% (27/39 cases). There were differences in the diagnostic sensitivity of the two methods (p=0.0224). Ultrasound combined with elastography demonstrated higher rates of conclusive and accurate diagnoses in patients with unexplained cervical lymphadenopathy than conventional ultrasound. The quantitative program showed good correlation with the pathology of different lymph node diseases.

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Ultrasound Elastography: Principles, Techniques, and Clinical Applications

Cited by 91 publications

References 0 publications

New imaging techniques for liver diseases

New imaging techniques for liver diseases

Value of ultrasound elastography in the diagnosis of native kidney fibrosis.

Clinical Value of Real Time Elastography in Patients with Unexplained Cervical Lymphadenopathy: Quantitative Evaluation

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