Ultrasonography in the staging of endometrial adenocarcinoma.

Requard, C K; Wicks, Jeffrey D.; Fa, Mettler

doi:10.1148/radiology.140.3.7280250

Cited by 37 publications

(11 citation statements)

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“…These features, along with uterine shape, endometrial thickness, echo pattern, and absence of the subendometrial halo, also can be used to distinguish between early and late stage uterine cancer. 9 Our study is in agreement that an enlarged uterus with a thickened echogenic endometrium is likely to be malignant. Thickened endometrial stripes have been extensively studied by Osmers and colleagues in a group of 386 postmenopausal women.…”

Section: Discussionsupporting

confidence: 90%

Gray scale and color flow Doppler characterization of uterine tumors.

Carter

Lau

Saltzman

et al. 1994

Journal of Ultrasound in Medicine

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The aim of this study was to investigate gray scale and color flow characteristics of a group of patients with a suspected uterine pathologic condition. One hundred and twenty-two consecutive patients at the Women's Cancer Center, University of Minnesota, undergoing transvaginal sonography and color flow Doppler imaging for suspected uterine corpus abnormality made up the study group. After gray scale morphologic assessment, color flow Doppler imaging of the tumor and uterus was performed, including the ipsilateral uterine artery. Malignant tumors were confirmed pathologically in all 35 patients who had them. In comparing patients with benign versus malignant tumors, gray scale morphologic assessment confirmed that malignant uterine tumors (31 endometrial cancers and four sarcomas) were more likely to have a thickened echoic endometrium (P = < 0.0001), be enlarged (P = 0.004), to be retroverted (P = 0.02), and to lack a subendometrial halo (P < 0.0001). Patients with four benign and 13 malignant tumors demonstrated increased flow when assessed by CFD. The calculated sensitivity of increased color flow in predicting malignancy was 39%, with a specificity of 92%, a positive predictive value of 77%, and a negative predictive value of 71%. No difference existed between the benign and malignant groups for the systolic, diastolic, and mean velocities and for the calculated pulsatility index and resistive index in both sampled uterine and intramyometrial or tumor vessels.(ABSTRACT TRUNCATED AT 250 WORDS)

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Section: Discussionsupporting

confidence: 90%

Gray scale and color flow Doppler characterization of uterine tumors.

Carter

Lau

Saltzman

et al. 1994

Journal of Ultrasound in Medicine

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“…In the study of 105 patients of endometrial carcinoma , done by Requad et al 5 , described no ultrasound criteria were diagnostic of carcinoma, there were statistically significant difference in the uterine shape and echo pattern between stage I -II and stage III & IV disease. 94% of patients with stage I -II had a normal or bulbous uterus and a normal or hypoechoic parenchymal pattern with a lobular uterus and /or mixed echo pattern had stage III & IV.…”

Section: Resultsmentioning

confidence: 98%

Real Time Ultrasonographic Evaluation of Gynecological Pelvic Masses - A Prospective Study

Kaushal¹,

Rajesh²

2013

jemds

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ABSTRACT:The space occupying lesions in female pelvis are very common over a wide age range. Many pathological conditions give rise to pelvic mass. It is difficult to arrive at an accurate diagnosis on clinical examination alone. Transabdominal and transvaginal ultrasonography are precisely helpful to determine the origin of a mass from uterus, ovaries, adnexal or extra genital structures. Serial sonographic examinations help in assessment of change in size and consistency for monitoring and for evaluation of therapeutic response. Aims: Sonographic evaluation of gynecological pelvic masses to determine the organ of origin, and correlation of sonographic diagnosis with histopathological examination. Method: A hospital based prospective study was done on 50 female patients with gynecological masses using high resolution ultrasonography and findings were correlated with histopathology examination. Result: Sonography was performed in 50 patients after a detailed clinical examination and various diagnoses were made. Patients were followed up to surgical management or serial sonographic monitoring in case of functional lesions. 52% patients were having uterine pathologies like leiomyoma, leiomyoma with pregnancy, adenomyosis, uterine and cervical malignancies, while 46% were having adnexal pathologies like benign ovarian cyst, malignant ovarian cyst, tubo-ovarian mass, cystic teratoma etc. and rest 2% were have other pathologies like localized pus collection in the pelvic cavity etc. Accuracy to identify organ of origin was 100% in the presenting study. In the identification of the uterine pathology, 91% of fibroid diagnosed correctly by ultrasonography while uterine and cervical malignancies were diagnosed with 100% accuracy in the presenting study. In various ovarian pathologies, benign cystic ovarian lesions were detected with 100% accuracy while malignant ovarian masses and tubo-ovarian masses were diagnosed with accuracy of 80% and 85% respectively. Conclusion: Ultrasonography is highly accurate in determining the organ of origin of gynecological pelvic mass. Sonographic

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“…This welt accepted procedure provides better endometrial echoes than abdominal scanning thanks to higher frequency probes and the nearness of the organ under study. Recent reports have shown it to be effective in (1) depicting invasion of the myometrium and (2) in the staging of advanced disease [1,4,8]. Since vaginosonography can be performed in the physician's office at practically no risk to the patient we wondered about its diagnostic capabilities in early disease.…”

Section: Introductionmentioning

confidence: 99%

Vaginosonography and its diagnostic value in patients with postmenopausal bleeding

Rudelstorfer¹,

Nanz²,

Bernaschek³

1990

Arch Gynecol Obstet

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Using a transvaginal 240 degrees "panorama" sector scanner (5.0 MHz) we performed a sonographic study in 106 women with postmenopausal bleeding before they had a diagnostic dilatation and curettage. Sonographic findings were classified as (1) normal thin endometrial echo, (2) pathologically thickened echo (i.e. more than 1/3 of the a.-p. diameter of the myometrial wall) and (3) spherical echoes representing myomas. We also looked carefully at the borders of the endometrium. 21 cases could not be included because of no histological specimen was available or because the vagina was too narrow for insertion of the probe. The histological and sonographic results were compared. Of 39 women with pathologically thickened endometrial echoes 12 had invasive carcinomas, 9 hyperplastic endometrium, 16 polyps and 2 had normal atrophic endometrium. In the 46 women with normal endometrial echoes 1 had a carcinoma (confined to the mucosa and obscured by a myoma), 1 had hyperplastic endometrium, 4 had small polyps (size below 5 mm) and 40 had normal atrophic endometrium.

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Ultrasonography in the staging of endometrial adenocarcinoma.

Cited by 37 publications

References 0 publications

Gray scale and color flow Doppler characterization of uterine tumors.

Gray scale and color flow Doppler characterization of uterine tumors.

Real Time Ultrasonographic Evaluation of Gynecological Pelvic Masses - A Prospective Study

Vaginosonography and its diagnostic value in patients with postmenopausal bleeding

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