Ultrasonographic measurement of the common carotid artery wall thickness in hypercholesterolemic patients A new model for the quantitation and follow-up of preclinical atherosclerosis in living human subjects

Normative values of carotid artery intima-media thickness in healthy Korean adults and estimation of macrovascular diseases relative risk using this data in type 2 diabetes patients

“…The correlation coefficients between IMT and age (r = 0.520 in healthy subjects; r = 0.429 in diabetic patients) were similar to previous studies [21][22][23]. Furthermore, the IMT appears to be primarily determined by age, systolic blood pressure, and BMI in healthy subjects.…”

Carotid Intimal-Medial Thickness and Stiffness Are Not Affected by Hypercholesterolemia in Uncomplicated Essential Hypertension

“…These data are partially in contrast with previous reports that indicated a role of hypercholesterolemia in inducing carotid intimal-medial thickening. 12,19,40 -44 However, 2 of these studies 19,42 included hypercholesterolemic patients with mild or moderate hypertension; moreover, diabetic patients and/or subjects with signs or symptoms of cardiovascular disease were not excluded. Nevertheless, although Poli et al 42 detected a significant increase in IMT in their hypercholesterolemic group, there was no significant correlation between carotid IMT and plasma cholesterol levels.…”

“…12,19,40 -44 However, 2 of these studies 19,42 included hypercholesterolemic patients with mild or moderate hypertension; moreover, diabetic patients and/or subjects with signs or symptoms of cardiovascular disease were not excluded. Nevertheless, although Poli et al 42 detected a significant increase in IMT in their hypercholesterolemic group, there was no significant correlation between carotid IMT and plasma cholesterol levels. In contrast, in the population described by Wendelhag et al, 19 the distribution of IMT in hypercholesterolemic patients appeared to be similar to that in normocholesterolemic subjects except for a few subjects in whom IMT values suggested the inclusion of plaques in the calculation.…”

“…[11][12][13][14][15] Moreover, carotid intimalmedial thickening has been described in association with hypertension 16,17 and hypercholesterolemia. 18,19 Studies of hypercholesterolemia have, however, included subjects with mild hypertension and/or symptomatic cardiovascular disease, and thus, they could not assess the independent contributions of uncomplicated hypertension and hypercholesterolemia to intimal-medial thickening.…”

Carotid artery compliance in users of plant stanol ester margarine

“…Increased carotid intima-media thickness correlates with vascular risk factors (Poli et al, 1988;Haapanen et al, 1989) and predicts cardiovascular events in population groups (Salonen and Salonen, 1991;Chambless et al, 1997;Hodis et al, 1998;Bots et al, 1999;O'Leary et al, 1999). A third commonly used marker of arterial health is brachial artery flow-mediated dilatation (Celermajer et al, 1992).…”