Ultrasensitive immunosensor for multiplex detection of cancer biomarkers carcinoembryonic antigen (CEA) and yamaguchi sarcoma viral oncogene homolog 1 (YES1) based on eco-friendly synthesized gold nanoparticles

Versatile Metal–Organic Framework Incorporating Ag2S for Constructing a Photoelectrochemical Immunosensor for Two Breast Cancer Markers

“…According to the principle of S/N = 3, the LOD , of an anodic PEC sensor is 0.014 U/mL, which is comparable with other strategies − for the detection of CA15-3 (Table S2). In contrast, for the cancer marker of CEA using a cathodic PEC sensor, the relationship is positively linear with the marker concentration, and the LOD is as low as 0.0023 ng/mL, which is superior to most methods − for sensing CEA (Table S3).…”

Split-type photoelectrochemical immunoassay for sensitive quantification of carcinoembryonic antigen based on target-induced in situ formation of Z-type heterojunction

“…4 An abnormal CEA concentration in serum implies that malignant carcinogenesis might occur in body tissues. 5 Therefore, developing sensitive and accurate sensing strategies for CEA detection is of practical significance. Up to now, various analytical approaches, such as fluorescence sensing, (photo-)electrochemical assay, surface-enhanced Raman scattering, and inductively coupled plasma mass spectrometry, 6–10 have been devised and applied for CEA detection.…”

A Novel Label-Free Electrochemical Immunosensor for the Detection of Thyroid Transcription Factor 1 Using Ribbon-like Tungsten Disulfide-Reduced Graphene Oxide Nanohybrids and Gold Nanoparticles

“…Over the past few years, electrochemical methods have been widely used in immunosensors due to their advantages, such as excellent specificity, good sensitivity and low cost [ 7 , 8 , 9 ]. Label-free electrochemical immunosensors in particular have attracted more attention, due to the ease involved with their operation, saving time and eliminating complex labeling processes when compared to sandwich-type immunosensors [ 10 , 11 , 12 ].…”