Ueber eine neue Synthese des Guanins und Xanthins

Abstract

Aus log 2.4.5-Triamino-6-oxy-pyrimidin erhiilt man 7-8 g Gnanin. Anglyee der bei 1200 getrockneten Verbindung: 0.2027g Sbst: 0.2929g COP, 0.0692g HoO.-0.1083 g Sbst.: 43.2c~m N (15.50, 755 mm).

Electrospray ionization mass spectrometric characterization and quantitation of xanthine derivatives using isotopically labelled analogues: an application for equine doping control analysis

“…In the past, several strategies for the synthesis of purines and substituted xanthines have been established 19–23. In order to introduce two triply deuterated methyl residues into the xanthine nucleus at positions N‐3 and N‐7, a published procedure for the generation of 7‐substituted 1‐methylxanthines24 was adapted and modified as follows: 156 mg of xanthine (1 mmol) were added to 40 mL of a mixture of MSTFA/ammonium iodide/ethanethiol (1000:2:6, v/w/v), which contains the in situ generated trimethyliodosilane (TMIS).…”

Thermal studies on metal complexes of 5-nitrosopyrimidine derivatives IV

“…The 6-amino-5-nitrosouracil (H2ANU) was synthesized in the Department of Organic Chemistry in Granada, using a previously described method [36]. All chemicals used were of analytical reagent grade or chemically pure.…”

8‐Oxo‐7,8‐dihydroadenine and 8‐Oxo‐7,8‐dihydroadenosine—Chemistry, Structure, and Function in RNA and Their Presence in Natural Products and Potential Drug Derivatives

“…[55,11] One century later,H irota et al used am ilder method to obtain functionalized 8-oxoAde analogues startingf rom triphosgene and various primary amines. [55,11] One century later,H irota et al used am ilder method to obtain functionalized 8-oxoAde analogues startingf rom triphosgene and various primary amines.…”

“…In 1900, Traube reported on the synthesis of 8-oxoAde via treatment of 4,5,6-triaminopyrimidine( dissolved in sodium hydroxide solutions) with phosgenea nd heat. [55,11] One century later,H irota et al used am ilder method to obtain functionalized 8-oxoAde analogues startingf rom triphosgene and various primary amines. [56] Kose tal.…”