Über die biologischen Wirkungen des weiblichen Sexualhormons

Steinach, E.; Dohrn, Max; Schoeller, W. R.; Hohlweg, W; Faure, W.

doi:10.1007/bf01723423

Cited by 20 publications

(6 citation statements)

References 12 publications

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“…Haterius (283) obtained hypertrophy of the mammary tissue of male guinea-pigs by the same treatment. Similar results on the ovariectomized guinea-pig have been reported by Steinach and co-workers (593).…”

Section: Clinical Resultssupporting

confidence: 90%

See 1 more Smart Citation

The Internal Secretions of the Ovary

Parkes¹

1931

The Journal of Nervous and Mental Disease

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Section: Clinical Resultssupporting

confidence: 90%

“…This process, and that of Zondek and Brahn, may be relied upon to give consistent results. Steinach and co-workers (593) report the preparation of a highly active aqueous extract, in which the end product is said to have an activity of 500 m.u. per c.c.…”

Section: {E) the Internal Secretion Complex Of The Ovarymentioning

confidence: 99%

The Internal Secretions of the Ovary

Parkes¹

1931

The Journal of Nervous and Mental Disease

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“…Er verwies insbesondere auf die Vernachlässigung der Wechselwirkung der Drüsen und Hormone durch Steinach. Darauf reagierte Steinach mit einem Aufsatz, in dem er überraschend betonte, sich bereits seit 1923 intensiv mit der Hormonforschung befasst zu haben (Steinach et al 1928). Allerdings beharrte er weiter auf dem Standpunkt, dass allein die Keimdrüsen über die Sexualentwicklung des Körpers entschieden.…”

Section: Die Verjüngungsdiskussion 1920 Bis 1925unclassified

Verjüngung und „Heilung” der Homosexualität

Mildenberger¹

2002

Z Sex-Forsch

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“…The power of oestrogenic hormones to inhibit lactation is, on the other hand, well established. The experiments of Laqueur et al (1928) Steinach et al (1928), Nelson (19353) and others have demonstrated that in the guinea-pig removal of the stimulus to mammary growth provided by oestrogenic hormones results in immediate iactation. Further, it has repeatedly been shown that administration of oestrogenic or gonadotrophic hormones to lactating animals results in inhibition of lactation.…”

Section: -2mentioning

confidence: 98%

Lactation

Folley¹

1940

Biological Reviews

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Summary 1. In most species oestrogens mainly stimulate mammary duct growth. In the guinea‐pig and goat they promote complete alveolar development. The mouse is the only animal in which treatment with progesterone has been found to promote mammary duct growth. In other species simultaneous treatment with oestrogens and progesterone is necessary for complete alveolar development. It is difficult to say whether or not oestrogens per se can promote alveolar development, because the adrenal cortex produces progesterone. 2. Androgens cause duct and alveolar growth in some species. 3. Some now believe that, under the influence of oestrogen, the anterior pituitary produces a “mammogenic” hormone which promotes mammary duct growth. 4. The presence of the anterior pituitary is essential for the initiation and maintenance of lactation. The anterior lobe is believed to secrete a specific lactogenic hormone (prolactin), but other anterior lobe hormones probably participate in the control of normal lactation. 5. Oestrogens may inhibit lactation during pregnancy, but it is probable that the pregnant uterus is also concerned in the inhibition. 6. The adrenal‐cortical hormone is necessary for lactation, since adrenal‐ectomized animals do not lactate, and, further, prolactin will not initiate or maintain lactation in hypophysectomized animals unless corticosterone or adrenotrophic hormone is also given. 7. The thyroid gland is essential for normal lactation: thyroxine stimulates nilk secretion in the cow. 8. Posterior pituitary extracts cause emptying of the bovine udder but do not affect the formation of milk. 9. Oestrogen treatment enriches milk in fatty and non‐fatty solids, and so does thyroxine treatment. Repeated injections of certain prolactin extracts increase the fat content of Cow's milk; certain other prolactin preparations increase the lactose content. 10. No true secretory nerves innervate the mammary gland. Lactation is disturbed in the cat if the sympathetic chains are extirpated. 11. The extraction of milk from the bovine udder depends on the reflex erection of udder tissues caused by stimulation of the teat, which also appears to cause the release of a lactogenic hormone or hormones from the hypophysis. 12. The mammary gland synthesizes lactose from blood glucose and also, probably, lactic acid. It is also possible that blood amino acids are de‐aminated by the mammary gland and used for lactose synthesis. 13. The precursor of milk fat is the neutral fat of the blood. The mammary gland probably oxidizes long‐chained fatty acids to the short‐chained acids of milk fat. 14. It is improbable that milk protein arises from blood amino acids. Plasma proteins are probably utilized for the synthesis of caseinogen, the phosphorus coming from the blood inorganic phosphate. 15. Various enzymes have been detected in active mammary tissue, which is a particularly rich source of the alkaline phosphomonoesterase. Changes in the secretory function of the mammary gland are usually accompanied by striking changes in the phosphomonoes...

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Über die biologischen Wirkungen des weiblichen Sexualhormons

Cited by 20 publications

References 12 publications

The Internal Secretions of the Ovary

The Internal Secretions of the Ovary

Verjüngung und „Heilung” der Homosexualität

Lactation

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