Type F Infant Botulism

Type F botulism due to neurotoxigenic Clostridium baratii from an unknown source in an adult

“…Because absorption of toxin probably takes place in the small intestine, much of the toxin may be inactivated before reaching the colon. Another strain of toxigenic C. baratii was previously described as the cause of a case of type F infant botulism in New Mexico (7,10). The cultural and physiological characteristics of that strain are identical to those of the organisms isolated in this investigation; the results of toxin neutralization tests for the two strains are also very similar.…”

Type F botulism due to neurotoxigenic Clostridium baratii from an unknown source in an adult

“…Because absorption of toxin probably takes place in the small intestine, much of the toxin may be inactivated before reaching the colon. Another strain of toxigenic C. baratii was previously described as the cause of a case of type F infant botulism in New Mexico (7,10). The cultural and physiological characteristics of that strain are identical to those of the organisms isolated in this investigation; the results of toxin neutralization tests for the two strains are also very similar.…”

Toxigenic clostridia

“…It has been isolated from normal infant stools (303), as well as from adult human and rat feces, war wounds, other clinical specimens, and from soil and sediment samples (54). The most striking finding with this organism was the implication of a neurotoxigenic strain as the cause of type F infant botulism (115,137). DNA relatedness studies confirmed the relationship of the neurotoxigenic strain to the type strain of C. baratii (312).…”

Infant Botulism: Anticipating the Second Decade

“…What makes this contribution even more remarkable is that the bacterium that produced the type E botulinal toxin was not C. botulinum, but was instead (by biochemical and chromatographic criteria) Clostridium butyricum [16]. This discovery enhances the significance of the recent report [17] of isolation of a Clostridium barati strain that produced type F botulinal toxin from a patient with infant botulism who was hospitalized in New Mexico in 1979 [18].…”

Type F botulism due to neurotoxigenic Clostridium baratii from an unknown source in an adult

“…Because absorption of toxin probably takes place in the small intestine, much of the toxin may be inactivated before reaching the colon. Another strain of toxigenic C. baratii was previously described as the cause of a case of type F infant botulism in New Mexico (7,10). The cultural and physiological characteristics of that strain are identical to those of the organisms isolated in this investigation; the results of toxin neutralization tests for the two strains are also very similar.…”

Toxigenic clostridia

“…It has been isolated from normal infant stools (303), as well as from adult human and rat feces, war wounds, other clinical specimens, and from soil and sediment samples (54). The most striking finding with this organism was the implication of a neurotoxigenic strain as the cause of type F infant botulism (115,137). DNA relatedness studies confirmed the relationship of the neurotoxigenic strain to the type strain of C. baratii (312).…”

Infant Botulism: Anticipating the Second Decade

“…What makes this contribution even more remarkable is that the bacterium that produced the type E botulinal toxin was not C. botulinum, but was instead (by biochemical and chromatographic criteria) Clostridium butyricum [16]. This discovery enhances the significance of the recent report [17] of isolation of a Clostridium barati strain that produced type F botulinal toxin from a patient with infant botulism who was hospitalized in New Mexico in 1979 [18].…”

Type F botulism due to neurotoxigenic Clostridium baratii from an unknown source in an adult

“…Because absorption of toxin probably takes place in the small intestine, much of the toxin may be inactivated before reaching the colon. Another strain of toxigenic C. baratii was previously described as the cause of a case of type F infant botulism in New Mexico (7,10). The cultural and physiological characteristics of that strain are identical to those of the organisms isolated in this investigation; the results of toxin neutralization tests for the two strains are also very similar.…”

Toxigenic clostridia

“…It has been isolated from normal infant stools (303), as well as from adult human and rat feces, war wounds, other clinical specimens, and from soil and sediment samples (54). The most striking finding with this organism was the implication of a neurotoxigenic strain as the cause of type F infant botulism (115,137). DNA relatedness studies confirmed the relationship of the neurotoxigenic strain to the type strain of C. baratii (312).…”

Infant Botulism: Anticipating the Second Decade

“…What makes this contribution even more remarkable is that the bacterium that produced the type E botulinal toxin was not C. botulinum, but was instead (by biochemical and chromatographic criteria) Clostridium butyricum [16]. This discovery enhances the significance of the recent report [17] of isolation of a Clostridium barati strain that produced type F botulinal toxin from a patient with infant botulism who was hospitalized in New Mexico in 1979 [18].…”