Clin Pediatr (Phila) volume 3, issue 1, P25-27 1964 DOI: 10.1177/000992286400300106 View full text
Martin Spector

Abstract: ETIULt~~~T ~~'~D PATHOGEIVESIS hE EARDRUM is composed of three lay-H' E EARDRUM is composed of three layers-an outer epithelial layer, a middle fibrous layer, and an inner mucosal layer. Most persistent perforations are due most commonly to chronic infection, and in these the epithelium has grown over the edges and prevented closure. The edges of such perforations appear white and thickened. Perforations at the drum margin or at the limbus tend to be the most resistant to closure.Perforations of the eardrum a…

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