Two macamide extracts relieve physical fatigue by attenuating muscle damage in mice

Zheng, Yue; Zhang, Wencheng; Wu, Zeyu; Fu, Chuan-Xiang; Hui, Ailing; Gao, Han; Chen, Peng-Peng; Du, Bin; Zhang, Huawei

doi:10.1002/jsfa.9318

Cited by 37 publications

(17 citation statements)

References 43 publications

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“…The warping mechanism has been briefly described above. Clearly, the arrangement of the molecular chains during the cooling process will significantly affect the warping degree of the product . Figure a shows melting curves of the PA6 blends containing different POE‐g‐MAH content.…”

Section: Resultsmentioning

confidence: 99%

“…And name them as 60‐40‐x (x refers to the weight fraction of PS in the blends, e.g., 60‐40‐05 represents the PS content in the PA6/POE‐g‐MAH/PS blend is 5 wt%). The other reason we choose PS is that PS is amorphous and the introduction will not lead to large shrinkage stress . Besides, the POE‐g‐MAH acting as a compatibilizer will give good compatibility between PA6 and PS .…”

Section: Resultsmentioning

confidence: 99%

“…Ultimately, serious warpage occurs. As is well known, a critical factor to the generation of shrinkage stresses is the crystallization of semi‐crystalline polymer, which has been reported by many researchers . In other words, the regular arrangement of molecular chains during the cooling process will significantly induce the shrinkage stress.…”

Section: Introductionmentioning

confidence: 99%

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Preparation of a new filament based on polyamide‐6 for three‐dimensional printing

Jia

Peng

et al. 2017

Polymer Engineering & Sci

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Fused deposition modeling (FDM) is one of the trendiest three-dimensional printing (3DP) technologies. However, FDM products based on virgin polyamide-6 (PA6) are seriously warped due to the accumulation of shrinkage stress generated from the crystallization of PA6. To solve this problem, maleic anhydride grafted poly(ethylene 1-octene) (POE-g-MAH) is added into PA6 to disturb the crystallization and reduce the shrinkage stress. Besides, rigid polystyrene (PS) with good flowability is further introduced to PA6/POE-g-MAH blend because too much addition of POE-g-MAH will weaken the PA6/POE-g-MAH, which will interrupt the printing process. The POE-g-MAH and PS both act as amorphous phase in the blends, which will reduce the shrinkage stress and is helpful to the shape stability of the printed products. Finally, a new kind of PA6-based filament with good toughness for FDM is prepared via this facile method.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Preparation of a new filament based on polyamide‐6 for three‐dimensional printing

Jia

Peng

et al. 2017

Polymer Engineering & Sci

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“…Tang et al (2019) relataram que além da ação antifadiga, ela pode ser usada como agente terapêutico e alimento funcional. Dessa forma também auxilia como ação protetora muscular após exercícios, retardando a fadiga muscular (Zheng et al, 2019).…”

Section: Resultsunclassified

Aplicações Terapêuticas Da Lepidium Meyenii (Maca) E Seus Compostos Químicos: Uma Revisão Sistemática / Therapeutic Applications of Lepidium Meyenii (Maca) and Its Chemical Compounds: A Systematic Review

Teixeira¹,

Santos²,

Bezerra³

et al. 2020

BJD

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RESUMO A Lepidium meyenii é uma planta nativa da região dos Andes, bastante utilizada em sua região devido ao alto valor nutricional dela, além de suas propriedades medicinais. Foi realizado uma revisão sistemática, a fim de identificar e analisar sobre a composição química e as atividades terapêuticas da Lepidium meyenii. Detectou-se nos estudos avaliados muitos benefícios dessa planta, alguns já eram esperados como ação antioxidante, antifadiga, anti-inflamatório, mas outras nos surpreenderam como as ações neuroprotetora, imunomoduladora, regulador hormonal entres outros efeitos terapêuticos. Estes fatos mudam a percepção e a importância dessa planta para a humanidade.

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“…The main chemical constituents of Maca are glucosinolates [ 13 , 14 , 15 ], macaenes, macamides [ 16 , 17 , 18 , 19 , 20 ], alkaloids [ 21 , 22 , 23 , 24 ], flavonols [ 25 ], phytosterols [ 14 ], polyscaccharides [ 26 ], and fatty acids. In our previous research, a series of pyrrole alkaloids [ 27 ] and thiohydantoin derivatives with cytotoxic and antimicrobial activities were found from Maca [ 28 , 29 ].…”

Section: Introductionmentioning

confidence: 99%

Macathiohydantoin L, a Novel Thiohydantoin Bearing a Thioxohexahydroimidazo [1,5-a] Pyridine Moiety from Maca (Lepidium meyenii Walp.)

et al. 2021

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Five new thiohydantoin derivatives (1–5) were isolated from the rhizomes of Lepidium meyenii Walp. NMR (1H and 13C NMR, 1H−1H COSY, HSQC, and HMBC), HRESIMS, and ECD were employed for the structure elucidation of new compounds. Significantly, the structure of compound 1 was the first example of thiohydantoins with thioxohexahydroimidazo [1,5-a] pyridine moiety. Additionally, compounds 2 and 3 possess rare disulfide bonds. Except for compound 4, all isolates were assessed for neuroprotective activities in corticosterone (CORT)-stimulated PC12 cell damage. Among them, compound (−)-3 exhibited moderate neuroprotective activity (cell viability: 68.63%, 20 μM) compared to the positive control desipramine (DIM) (cell viability: 88.49%, 10 μM).

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Two macamide extracts relieve physical fatigue by attenuating muscle damage in mice

Abstract: Two macamide extracts have a beneficial effect on relieving physical fatigue by attenuating the damage of skeletal muscle and myocardium during exercise, and a better effect was observed in the PME group. © 2018 Society of Chemical Industry.

Cited by 37 publications

References 43 publications

Preparation of a new filament based on polyamide‐6 for three‐dimensional printing

Preparation of a new filament based on polyamide‐6 for three‐dimensional printing

Aplicações Terapêuticas Da Lepidium Meyenii (Maca) E Seus Compostos Químicos: Uma Revisão Sistemática / Therapeutic Applications of Lepidium Meyenii (Maca) and Its Chemical Compounds: A Systematic Review

Macathiohydantoin L, a Novel Thiohydantoin Bearing a Thioxohexahydroimidazo [1,5-a] Pyridine Moiety from Maca (Lepidium meyenii Walp.)

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