Two-Dimensional Strain–A Doppler-Independent Ultrasound Method for Quantitation of Regional Deformation: Validation In Vitro and In Vivo

Kořínek, Josef; Wang, Jianwen; Sengupta, Partho P.; Miyazaki, Chinami; Kjærgaard, Jesper; McMahon, Eileen; Abraham, Theodore P.; Bělohlávek, Marek

doi:10.1016/j.echo.2005.03.024

Cited by 332 publications

(224 citation statements)

References 13 publications

Supporting

Mentioning

205

Contrasting

Unclassified

Order By: Relevance

“…These patterns can be used for motion analysis (speckle tracking) (30). The anisotropic structure of the LV wall, with fiber directions changing from a right-handed helix in the subendocardium to a left-handed helix in the subepicardium ( Fig.…”

Section: Effect Of Myocardial Anisotropy On Appearance Of Cardiac Ultmentioning

confidence: 99%

Left Ventricular Form and Function Revisited: Applied Translational Science to Cardiovascular Ultrasound Imaging

Sengupta

Krishnamoorthy

Kořínek

et al. 2007

Journal of the American Society of Echocardiography

Self Cite

283

196

View full text Add to dashboard Cite

Tissue Doppler imaging (TDI) and TDI-derived strain imaging are robust physiologic tools used for the noninvasive assessment of regional myocardial function. Due to high temporal and spatial resolution, regional function can be assessed for each phase of the cardiac cycle and within the transmural layers of the myocardial wall. Newer techniques that measure myocardial motion by speckle tracking in grayscale images have overcome the angle dependence of TDI strain, allowing for measurement of 2-dimensional strain and cardiac rotation. TDI, TDI strain, and speckle tracking may provide unique information that deciphers the deformation sequence of complexly oriented myofibers in the left ventricular wall. The data are, however, limited. This review examines the structure and function of the left ventricle relative to the potential clinical application of TDI and speckle tracking in assessing the global mechanical sequence of the left ventricle in vivo.The spiral arrangement of muscle fibers in the heart is reminiscent of spiral and vortex patterns in nature, ranging from small organelles and whirlpools to hurricanes and rotational patterns of the galaxies (1-5). Vortex patterns link two fundamental forms of motion that work in close balance: an inner, rapidly descending swirl and an outer, less rapid, ascending rotation (4) ( Fig. 1 A-C). These counterdirectional movements of a vortex produce suction and expulsion forces that have been exploited for designing energy efficient propellers and turbines (6). Likewise, experimental and mathematical modeling of the clockwise and counterclockwise spiral loops of myofibers in the left ventricle (LV) has shown that counterdirectional geometry provides an efficient distribution of regional stresses and strains (7). Conversely, altered ventricular geometry resulting from cardiac remodeling, regional myocardial dysfunction, or asynchronous conduction distort the efficiency of the loading and expulsion dynamics (8,9). In this review, we associate the LV myofiber architecture to the spatiotemporal sequence of regional deformations occurring during normal cardiac contraction and relaxation. We further elucidate experimental observations, which explore the application of tissue Doppler imaging (TDI) and 2-dimensional ultrasound speckle tracking for delineation of the synchronous mechanical shortening and lengthening sequences of the human LV.Address reprint requests to Marek Belohlavek, Division of Cardiovascular Diseases, Mayo Clinic, 13400 East Shea Boulevard Scottsdale, AZ 85259, E-mail address for author named in reprint line: Belohlavek.marek@mayo.edu Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect th...

show abstract

Section: Effect Of Myocardial Anisotropy On Appearance Of Cardiac Ultmentioning

confidence: 99%

Left Ventricular Form and Function Revisited: Applied Translational Science to Cardiovascular Ultrasound Imaging

Sengupta

Krishnamoorthy

Kořínek

et al. 2007

Journal of the American Society of Echocardiography

Self Cite

283

196

View full text Add to dashboard Cite

show abstract

“…25 A recent Spanish study on 237 saphenous graft stenoses treated by DES or bare-metal stent (BMS) concluded a similar 30-month prognosis for both groups. 26 Another study analyzed outcomes after PCI for patients with a history of CABG versus no history of CABG found that post-CABG patients had higher levels of event at 6 months, including death and MI, an outcome that was poorer for percutaneous transluminal coronary angioplasty (PTCA) in grafts versus native lesions. This poorer outcome could not be explained only by the patients' baseline characteristics, but also because graft PCI was difficult and the lesions were complex and contained more luminal thrombi.…”

Section: Prognosismentioning

confidence: 99%

Can We Improve Outcomes in Patients With Previous Coronary Artery Bypass Surgery Admitted for Acute Coronary Syndrome?

Teixeira

Lourenço

António

et al. 2010

Revista Española de Cardiología (English Edition)

View full text Add to dashboard Cite

“…2D-STE is an automated and quantitative technique for the measurement of cardiac mechanics, which is based on the speckle interference of ultrasound beams within tissues. Speckles are tracked on a frame-by-frame basis throughout the cardiac cycle [23], which has more advantages than conventional echocardiography, including angle independency, free of tethering and transla- tion effects, low signal-to-noise ratio, and low measurement variability [24,25]. Systolic dysfunction might initially appear in the longitudinal direction, as the longitudinally oriented subendocardial fibers are more vulnerable to myocardial ischemia and fibrosis.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of left ventricular function after percutaneous recanalization of chronic coronary occlusions

Wang

Liu

Ren

2018

Herz

View full text Add to dashboard Cite

Evaluation of left ventricular function after percutaneous recanalization of chronic coronary occlusionsThe role of two-dimensional speckle tracking echocardiography Chronic total occlusion (CTO) is defined as an occluded coronary artery presenting as thrombolysis in myocardial infarction (TIMI) with grade 0 or 1 flow in a recent myocardial infarction (MI) [1,2]. The myocardium in the perfusion territory of a CTO can be functional, dysfunctional but viable, or dysfunctional and nonviable [3,4]. Dysfunctional but viable myocardium in CTO may have restored function after percutaneous coronary intervention (PCI) [5][6][7][8][9]. However, the earliest time that the recovery of dysfunctional but viable myocardium can be detected remains unknown. Conventional echocardiography enables us to identify significant left ventricular (LV) dysfunction but not subclinical dysfunction [10]. Two-dimensional speckle tracking echocardiography (2D-STE) allows for an angle-independent evaluation of myocardial strain, and provides comprehensive information on LV myocardial contractility. Thus, 2D-STE is superior in detecting subtle deteriorations of contractility [11][12][13]. These advantages of 2D-STE are useful for the detection of subclinical recovery of dysfunctional but viable myocardium after CTO-PCI.In this study, the LV systolic function of CTO patients with dysfunctional myocardium was evaluated at 1 day as well as 3 and 6 months after percutaneous revascularization using 2D-STE. It was found that 2D-STE was superior in detecting subclinical LV systolic dysfunction in CTO patients after percutaneous revascularization. Patients and methods SubjectsA single-center prospective observational study was performed from July 2012 to March 2016. Patients with CTO with an estimated duration of less than 3 months or an MI during the previous 30 days were excluded, but no other predefined clinical inclusion or exclusion criteria were applied. The indication for PCI was determined by individual investigators at the participating center. In all, 43 patients (mean age: 66.09 ± 10.99 years) scheduled to undergo PCI for CTO in a native coronary artery were eligible for enrollment. Among them, there were 40 males and three females. The CTO of ten patients was located in the left anterior descending artery in ten patients, in the right coronary artery in 25 patients, and in the circumflex artery in eight patients. A follow-up visit or telephone interview was scheduled at 1 day as well as 3 and 6 months after percutaneous revascularization. Prior written and informed consent was obtained from every patient. This study was approved by the Ethics Review Board of Capital Medical University. Percutaneous revascularizationPercutaneous revascularization was performed by operators highly experienced in the treatment of CTO according to their standard practices with the femoral or brachial approach. The operation was considered successful when the residual stenosis was ≤30% of the intraluminal diameter, with TIMI grade 3 flow and no inhospital complic...

show abstract

Two-Dimensional Strain–A Doppler-Independent Ultrasound Method for Quantitation of Regional Deformation: Validation In Vitro and In Vivo

Cited by 332 publications

References 13 publications

Left Ventricular Form and Function Revisited: Applied Translational Science to Cardiovascular Ultrasound Imaging

Left Ventricular Form and Function Revisited: Applied Translational Science to Cardiovascular Ultrasound Imaging

Can We Improve Outcomes in Patients With Previous Coronary Artery Bypass Surgery Admitted for Acute Coronary Syndrome?

Evaluation of left ventricular function after percutaneous recanalization of chronic coronary occlusions

Contact Info

Product

Resources

About