Two cases of focal status epilepticus in pregnancy

Abstract

Highlights Two pregnant women with a history of epilepsy were found in focal status epilepticus. VEEG and fetal heart tracing were examined simultaneously with the patient’s seizures. The patient in Case 1 was treated more conservatively than Case 2 despite similar findings on FHT. Case 1 eventually stopped seizing while Case 2 developed complications related to ASM treatment. How can we incorporate FHT during the management of pregnant women with seizures?

The pharmacologic management of status epilepticus in pregnant patients: a scoping review

“…10 Several studies in the literature cited dramatic improvement in seizure management following delivery of the infant, if this was deemed to be a reasonable approach based on the progress of the pregnancy. 23,24,29,31 In this study, almost all maternal outcomes were positive. This may have been due to the limited number of patients reported, decreasing the likelihood of detection of negative outcomes, as well as publication bias.…”

“…This may be attained through the judicious use of ASM therapy and/or delivery of the infant, if feasible 10 . Several studies in the literature cited dramatic improvement in seizure management following delivery of the infant, if this was deemed to be a reasonable approach based on the progress of the pregnancy 23,24,29,31 . In this study, almost all maternal outcomes were positive.…”

The pharmacologic management of status epilepticus in pregnant patients: a scoping review

“…10 Several studies in the literature cited dramatic improvement in seizure management following delivery of the infant, if this was deemed to be a reasonable approach based on the progress of the pregnancy. 23,24,29,31 In this study, almost all maternal outcomes were positive. This may have been due to the limited number of patients reported, decreasing the likelihood of detection of negative outcomes, as well as publication bias.…”

“…This may be attained through the judicious use of ASM therapy and/or delivery of the infant, if feasible 10 . Several studies in the literature cited dramatic improvement in seizure management following delivery of the infant, if this was deemed to be a reasonable approach based on the progress of the pregnancy 23,24,29,31 . In this study, almost all maternal outcomes were positive.…”

Status Epilepticus and Low-Grade Glioma in the Pregnant State: Case Report and Ethical Considerations

“…Status Epilepticus in Pregnancy SE is a neurological emergency with a mortality rate between 10 and 15% [8]. Although scarce, there have been reports of SE in pregnancy (SEP); most of these cases can be attributed, directly or indirectly, to the physiological changes encountered during pregnancy [6,8,[10][11][12]. For example, eclampsia, cerebral venous thrombosis, posterior reversible encephalopathy syndrome, and increased glomerular filtration rates (which decrease ASM levels in patients with preexisting epilepsy) have all been described in the literature [6].…”

The pharmacologic management of status epilepticus in pregnant patients: a scoping review

“…10 Several studies in the literature cited dramatic improvement in seizure management following delivery of the infant, if this was deemed to be a reasonable approach based on the progress of the pregnancy. 23,24,29,31 In this study, almost all maternal outcomes were positive. This may have been due to the limited number of patients reported, decreasing the likelihood of detection of negative outcomes, as well as publication bias.…”

“…This may be attained through the judicious use of ASM therapy and/or delivery of the infant, if feasible 10 . Several studies in the literature cited dramatic improvement in seizure management following delivery of the infant, if this was deemed to be a reasonable approach based on the progress of the pregnancy 23,24,29,31 . In this study, almost all maternal outcomes were positive.…”

Status Epilepticus and Low-Grade Glioma in the Pregnant State: Case Report and Ethical Considerations

“…Status Epilepticus in Pregnancy SE is a neurological emergency with a mortality rate between 10 and 15% [8]. Although scarce, there have been reports of SE in pregnancy (SEP); most of these cases can be attributed, directly or indirectly, to the physiological changes encountered during pregnancy [6,8,[10][11][12]. For example, eclampsia, cerebral venous thrombosis, posterior reversible encephalopathy syndrome, and increased glomerular filtration rates (which decrease ASM levels in patients with preexisting epilepsy) have all been described in the literature [6].…”

The pharmacologic management of status epilepticus in pregnant patients: a scoping review

“…10 Several studies in the literature cited dramatic improvement in seizure management following delivery of the infant, if this was deemed to be a reasonable approach based on the progress of the pregnancy. 23,24,29,31 In this study, almost all maternal outcomes were positive. This may have been due to the limited number of patients reported, decreasing the likelihood of detection of negative outcomes, as well as publication bias.…”

“…This may be attained through the judicious use of ASM therapy and/or delivery of the infant, if feasible 10 . Several studies in the literature cited dramatic improvement in seizure management following delivery of the infant, if this was deemed to be a reasonable approach based on the progress of the pregnancy 23,24,29,31 . In this study, almost all maternal outcomes were positive.…”

Status Epilepticus and Low-Grade Glioma in the Pregnant State: Case Report and Ethical Considerations

“…Status Epilepticus in Pregnancy SE is a neurological emergency with a mortality rate between 10 and 15% [8]. Although scarce, there have been reports of SE in pregnancy (SEP); most of these cases can be attributed, directly or indirectly, to the physiological changes encountered during pregnancy [6,8,[10][11][12]. For example, eclampsia, cerebral venous thrombosis, posterior reversible encephalopathy syndrome, and increased glomerular filtration rates (which decrease ASM levels in patients with preexisting epilepsy) have all been described in the literature [6].…”