Two cases of cutaneous eruptions due to CoVID‐19 infection in Singapore: new insights into the spectrum of clinical presentation and histopathology

Ho, Weiguang; Wang, D.; Tan, Lei; Bundele, Manish Mahadeorao; Tan, Chianru; Lim, H.L.J.

doi:10.1111/jdv.16736

Cited by 6 publications

(1 citation statement)

References 6 publications

(7 reference statements)

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“…There were early case reports of maculopapular exanthem, skin conditions from prolonged PPE usage, and hand dermatitis, but chilblainslike lesions were rare. 42 …”

Section: Introductionmentioning

confidence: 99%

How Coronavirus Disease 2019 Changed Dermatology Practice in 1 Year Around the World

Sun

McMahon

Ugwu‐Dike

et al. 2021

Dermatologic Clinics

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Coronavirus disease 2019 (COVID-19) brought the world to its knees. As each nation grappled with launching an effective response while simultaneously minimizing repercussions on health care systems, economies, and societies, the medical and scientific landscape shifted forever. In particular, COVID-19 has challenged and transformed the field of dermatology and the way we practice. In this article, dermatologists from 11 countries share insights gained from local experience. These global perspectives will help provide a better framework for delivering quality dermatologic care and understanding how the field has evolved during this medical crisis.

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“…There were early case reports of maculopapular exanthem, skin conditions from prolonged PPE usage, and hand dermatitis, but chilblainslike lesions were rare. 42 …”

Section: Introductionmentioning

confidence: 99%

How Coronavirus Disease 2019 Changed Dermatology Practice in 1 Year Around the World

Sun

McMahon

Ugwu‐Dike

et al. 2021

Dermatologic Clinics

View full text Add to dashboard Cite

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Skin manifestations of COVID-19: A worldwide review

Tan¹,

Tam²,

Oh³

2021

JAAD International

120

144

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Introduction Because of the increasing emergence of skin manifestations of the coronavirus disease 2019 (COVID-19) worldwide, we investigated the published reports of these lesions. Methods We conducted a literature search for original and review articles published from November 11, 2019, to September 30, 2020. Results We determined five skin lesions common in patients with COVID-19: pseudo-chilblains, maculopapular, urticarial, vesicular, and vaso-occlusive lesions. These lesions manifest at various times in relation to COVID-19 symptoms, which may indicate whether the lesions are virus-induced or are delayed immunological responses to the infection. Skin lesions are more prevalent among Europeans and US residents than among Asians, as is pseudo-chilblain, and the morphology of the skin lesions varies between continents. Pseudo-chilblains are the most common COVID-19 skin manifestation in Europe and the United States, but there is only one reported case from Asian populations. Additionally, patients with vaso-occlusive lesions are more likely than those with pseudo-chilblains to be admitted to the intensive care unit and to die. Conclusion Different cutaneous manifestations in patients with COVID-19 could reflect a wide spectrum of viral interactions with the skin, though reporting bias may play a role as well.

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Histopathological and Immunohistochemical Characterization of Skin Biopsies From 41 SARS-CoV-2 (+) Patients: Experience in a Mexican Concentration Institute: A Case Series and Literature Review

Quintero-Bustos

Aguilar‐León

Saeb‐Lima

2022

The American Journal of Dermatopathology

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:The SARS-CoV-2 pandemic brought countless clinical and pathophysiological questions. Although mucocutaneous infections are the most visible, they are among the least studied. This article provides relevant information to characterize morphologically and immunohistochemically the dermatoses from patients with COVID-19, during the first year of the pandemic. Immunohistochemistry reactions against the spike protein were performed in 48 skin biopsies, and the positive cases were classified according to their histomorphology; at the end, 41 biopsies led us to identify 12 morphological patterns that mimic other skin pathologies, among which pityriasiform patterns predominate. For the literature review, we selected cases of SARS-CoV-2 dermatoses that included complete histopathological information and that were published during the same interval of time; after careful evaluation, 205 biopsies were selected and then classified into 8 groups according to previously published proposals. Dermatoses associated with SARS-CoV-2 are as diverse in their clinical expression as in their histopathology, mimicking entities totally unrelated to COVID-19. Furthermore, some of these groups are characteristically associated with an aggressive course of the disease. Undoubtedly, it is necessary to delve into the possibility that these findings are translatable into prognostic and therapeutic factors.

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Two cases of cutaneous eruptions due to CoVID‐19 infection in Singapore: new insights into the spectrum of clinical presentation and histopathology

Cited by 6 publications

References 6 publications

How Coronavirus Disease 2019 Changed Dermatology Practice in 1 Year Around the World

How Coronavirus Disease 2019 Changed Dermatology Practice in 1 Year Around the World

Skin manifestations of COVID-19: A worldwide review

Histopathological and Immunohistochemical Characterization of Skin Biopsies From 41 SARS-CoV-2 (+) Patients: Experience in a Mexican Concentration Institute: A Case Series and Literature Review

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