Twenty years of experience with PDD and PDT in Poland—Review

Sieroń, Aleksander; Kwiatek, Sebastian

doi:10.1016/j.pdpdt.2009.07.003

Cited by 20 publications

(15 citation statements)

References 37 publications

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“…Many advantages resulting from cooperation between laboratory and clinical researchers have been raised by Sieroń and Kwiatek [5], who summarized laboratory and clinical research on PDT and photodynamic diagnosis (PDD) in Poland. Benefits resulting from cooperation between various specialists have been noted for several years of PDT treatment in Brazil, stressing that the cooperation between specialists helps to improve the results and the quality of treatment.…”

Section: Photomedicine -Advances In Clinical Practicementioning

confidence: 99%

“…One of the most important issues is also the reduction or overcoming of the adverse effects caused by photosensitizers such as photosensitivity lasting up to several weeks after treatment or elimination of pain associated with treatment [20]. Sieroń and Kwiatek [5] discussed the work carried out by an interdisciplinary team consisting of physicists and chemists, whose aim was to develop an optimal structure of a novel photosensitizer. They performed chemical synthesis in a novel potential photosensitizer and its physicochemical characterization with the detailed assessment of spectroscopic properties.…”

Section: Photomedicine -Advances In Clinical Practicementioning

confidence: 99%

“…Further studies on cell and molecular aspects of PDT action with the newly elaborated photosensitizers are necessary on various cells in vitro and in vivo tumor models. All these studies can help to explore cytotoxicity, photocytotoxicity, and genotoxicity of novel photosensitizers [5,33]. Considering the relevant aspects of medicinal chemistry and pharmaceutical chemistry important in various stages of preclinical trials, the pharmacist's expertise can also be very useful.…”

Section: Photomedicine -Advances In Clinical Practicementioning

confidence: 99%

“…Unfortunately, ALA-PDT treatment has certain drawbacks. One of them is low skin permeability, limiting this treatment only to surface skin lesions, e.g., malignant skin tumors [5,20].…”

Section: Pharmacistsmentioning

confidence: 99%

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Nurses and Pharmacists in Interdisciplinary Team of Health Care Providers in Photodynamic Therapy

Kocki¹,

Czarczyńska-Goślińska²,

Kocka³

et al. 2017

Photomedicine - Advances in Clinical Practice

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Background: The modern treatment is based on wide cooperation between diverse representatives of medical professions. The photodynamic therapy is a noninvasive method of treatment both neoplastic diseases and miscellaneous noncancerous illnesses. It is complementary and competitive in some way to various traditional treatment techniques, including chemotherapy, radiotherapy, and surgery. This review emphasizes the significance of collaboration between specialists engaged in research, development, and practical use of photodynamic therapy.Methods: A literature search of electronic bibliographic databases and scientific publishers was performed. The relevant literature was analyzed to identify articles on the involvement of nurses, pharmacists, physicians, and other representatives in photodynamic therapy treatment.Results: In the photodynamic therapy, the overall success is not only dependent of a single unit. Coordinated actions of representatives possessing expertise in various fields of medical, and natural sciences are necessary both during joint research, development, and during the course of the photodynamic therapy treatment in clinics. Conclusions:The effective interaction between professionals and the division of responsibilities at different stages of therapy can guarantee the successful treatment. During therapy, the most important role belongs to the patient who is responsible for acting in accordance with schedules elaborated by physicians, nurses, and pharmacists.

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Section: Photomedicine -Advances In Clinical Practicementioning

confidence: 99%

Section: Photomedicine -Advances In Clinical Practicementioning

confidence: 99%

Section: Photomedicine -Advances In Clinical Practicementioning

confidence: 99%

“…Unfortunately, ALA-PDT treatment has certain drawbacks. One of them is low skin permeability, limiting this treatment only to surface skin lesions, e.g., malignant skin tumors [5,20].…”

Section: Pharmacistsmentioning

confidence: 99%

See 2 more Smart Citations

Nurses and Pharmacists in Interdisciplinary Team of Health Care Providers in Photodynamic Therapy

Kocki¹,

Czarczyńska-Goślińska²,

Kocka³

et al. 2017

Photomedicine - Advances in Clinical Practice

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“…O diagnóstico fotodinâmico surgiu como uma importante ferramenta diagnóstica, por ser uma técnica rápida, de fácil realização, não invasiva, seletiva e sensível (SIERON et al, 2013). Muitas aplicações desse método têm sido discutidas em diferentes áreas médicas, como a dermatologia, gastroenterologia, odontologia, pneumologia, ortopedia, urologia, neurologia e principalmente na oncologia (SIERON & KWIATEK, 2009;WOLUN-CHOLEWA et al, 2011;AHMAD et al, 2012;CHEUNG et al, 2013;BORRONI et al, 2015;YAMAMOTO et al, 2015).…”

Section: Introductionunclassified

Diagnóstico Fotodinâmico: Princípios E Aplicações

Oliveira¹,

Teles²,

Bezerra³

et al. 2015

Enciclopédia Biosfera

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RESUMONos últimos anos, houve um crescimento na utilização de técnicas baseadas em fluorescência. Entretanto, na Medicina Veterinária tais técnicas são pouco difundidas e utilizadas. Diante da necessidade de um maior esclarecimento na utilização dessas técnicas para auxiliar o diagnóstico de enfermidades, o objetivo principal deste trabalho foi englobar as principais aplicações do fotodiagnóstico, bem como os fotossensibilizadores mais utilizados neste processo. O diagnóstico fotodinâmico baseia-se na forma em que tecidos normais e anormais absorvem a luz, permitindo então a visualização de fluorescência diferencial nestes tecidos quando em contato com fluoróforos. Estes fluoróforos podem ser endógenos ou exógenos, e emitem fluorescência ao serem excitados por um comprimento de onda específico da luz visível dentro da gama do espectro. Os fluoróforos exógenos são chamados de fotossensibilizadores e possuem um papel fundamental no fotodiagnóstico, pois são moléculas capazes de interagir com luz e gerar fluorescência ou espécies reativas do oxigênio. Esta técnica pode ser aplicada para o diagnóstico de diversas enfermidades, como, por exemplo, no diagnóstico de fungos de pele, na detecção da cárie dentária, cálculos e biofilmes bacterianos, na detecção de pequenas lesões no trato digestório e principalmente no diagnóstico precoce do câncer e no tratamento de neoplasias. Por ser uma técnica inovadora, que apresenta uma alta sensibilidade e especificidade, não ser invasiva, além de ser uma técnica rápida e de fácil realização, o diagnóstico fotodinâmico apresenta um enorme potencial de utilização na Medicina Veterinária.

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