“…Turbulence is a crucial feature observed in plasma flow that arises due to changes in vessel physiology. 24 Such changes in plasma flow caused by vascular dynamics could potentially affect the distribution of proteins in the blood and their interactions with NPs. 25 A classic example of how vessel structure affects the flow and its implications is the increased probability of plaque depositions and leukocyte adhesion at vessel bifurcations.…”
The protein corona (PC) that forms on nanoparticles (NPs) after in vivo injection influences their biodistribution, pharmacokinetics, and cell interaction. Although injected NPs traverse vascular networks, the impact of vascular...
“…Turbulence is a crucial feature observed in plasma flow that arises due to changes in vessel physiology. 24 Such changes in plasma flow caused by vascular dynamics could potentially affect the distribution of proteins in the blood and their interactions with NPs. 25 A classic example of how vessel structure affects the flow and its implications is the increased probability of plaque depositions and leukocyte adhesion at vessel bifurcations.…”
The protein corona (PC) that forms on nanoparticles (NPs) after in vivo injection influences their biodistribution, pharmacokinetics, and cell interaction. Although injected NPs traverse vascular networks, the impact of vascular...
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