Tuning the phase transition temperature of hybrid Span60-L64 thermoresponsive niosomes: Insights from fluorescence and Raman spectroscopy

Dual Stimuli-Responsive BSA-Protected Silver Nanocluster-Driven “FRET On–Off” within the Niosomal Membrane: An Amalgamation of Restoration of Aggregation-Induced Quenched Fluorescence and Energy Transfer

“…Interestingly, we found a linear decrease in the steady-state fluorescence anisotropy although there is no phase change in the niosomal membrane (Figure S7D). We attribute this to the possibility of formation of some microscopic disordered bilayer regions where the free volume space inside the hydrocarbon chains of the surfactants increases according to a previous report and imparts stability to C6 by relaxing the structural restraints, leading to a blue shift of the absorption maximum and enhancement in the PL intensity with a linear decrease in anisotropy. The maximum relative sensitivity of C6 was found to be around 0.9% K –1 at 35 °C in the niosomal membrane (Figure S7E).…”

Brij Niosomes as Carriers for Sustained Drug Delivery─A Fluorescence-Based Approach to Probe the Niosomal Microenvironment

“…Earlier, some workers have studied phospholipid monolayer or bilayers using the fluorescence techniques . Few studies have focused on fluorescence methods to probe niosomes. − Different fluorescent probes/dyes have been used to follow the changes in the niosomal structure and bilayer integrity of the niosomes under varying conditions of hydrophobicity/hydrophilicity (achieved by using different surfactants).The polarity probe C-153 and the membrane-binding probe 1,6-diphenyl-1,3,5-hexatriene (DPH) have been used to study the changes in the niosomal bilayer under stress conditions.…”

Exploring the membrane fluidity of phenyl boronic acid functionalized polymersomes using the FRAP technique and their application in the pH-sensitive release of curcumin

“…The structure of the polymersomes is depicted from the literature. 11,49 The successful formation of the CUR-loaded vesicles was confirmed by confocal and SEM studies. From Fig.…”

“…Targeted drug-delivery treatment can be achieved by a stimuli-responsive DDS through functionalizing the ligands, which can facilitate drug delivery to the tumour cells. [11][12][13][14][15] This treatment is based on the strategy where the overexpression of antigens or receptors differentiates tumour cells from normal cells, facilitating the binding of a ligand-conjugated DDS to the tumour cells. This strategy increases the drug residence at the target site, leading to a higher cellular uptake and intra-cellular stability with minimum unsought side effects; thereby resulting in a higher therapeutic efficiency.…”