Liquid drops sliding on tilted surfaces is an everyday phenomenon and is important for many industrial applications. Still, it is impossible to predict the drop’s sliding velocity. To make a step forward in quantitative understanding, we measured the velocity $$(U)$$
(
U
)
, contact width $$(w)$$
(
w
)
, contact length $$(L)$$
(
L
)
, advancing $$({\theta }_{{{{{{\rm{a}}}}}}})$$
(
θ
a
)
, and receding contact angle $$({\theta }_{{{{{{\rm{r}}}}}}})$$
(
θ
r
)
of liquid drops sliding down inclined flat surfaces made of different materials. We find the friction force acting on sliding drops of polar and non-polar liquids with viscosities ($${\eta }$$
η
) ranging from 10−3 to 1 $${{{{{\rm{Pa}}}}}}\cdot {{{{{\rm{s}}}}}}$$
Pa
⋅
s
can empirically be described by $${F}_{{{{{{\rm{f}}}}}}}(U)={F}_{0}+\beta w\eta U$$
F
f
(
U
)
=
F
0
+
β
w
η
U
for a velocity range up to 0.7 ms−1. The dimensionless friction coefficient $$(\beta )$$
(
β
)
defined here varies from 20 to 200. It is a material parameter, specific for a liquid/surface combination. While static wetting is fully described by $${\theta }_{{{{{{\rm{a}}}}}}}$$
θ
a
and $${\theta }_{{{{{{\rm{r}}}}}}}$$
θ
r
, for dynamic wetting the friction coefficient is additionally necessary.