1994
DOI: 10.1002/hed.2880160103
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Tumors of the skull base: Outcome and survival analysis of 77 cases

Abstract: We reviewed our experience with combined approaches to lesions that transcend the bones of the skull base. Seventy-seven skull base procedures were performed on 73 patients during a 10-year period from 1982 to 1992. There were 34 patients (44%) with region lesions (anterior), seven patients (9%) with region II lesions (anterior-lateral), 25 patients (32%) with region III lesions (lateral-posterior), and 11 patients (14%) with lesions that invaded more than one anatomic site. The histopathology in this series w… Show more

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Cited by 144 publications
(125 citation statements)
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“…Apesar deste avanço, a recidiva tumoral ainda ocorre em 32% dos casos após a abordagem craniofacial 10 . Em nossa série, a taxa de recidiva foi de 7,1%.…”
Section: Discussionunclassified
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“…Apesar deste avanço, a recidiva tumoral ainda ocorre em 32% dos casos após a abordagem craniofacial 10 . Em nossa série, a taxa de recidiva foi de 7,1%.…”
Section: Discussionunclassified
“…Entretanto, a reparação com retalhos livres reduz a morbidade cirúrgica das ressecções craniofaciais 6,[12][13][14] . A taxa de complicação de 58,6% é semelhante às encontradas na literatura, que variam de 16 a 64% 8,10,13,15 . As infecções locais ocorreram em 21,7% dos casos, sendo a complicação mais comum, talvez justificada pela inclusão em nossa avaliação de complicações locais como deiscências e infecções restritas, ou ao freqüente estado geral seriamente comprometido destes pacientes , seja pela gravidade da doença ou pelo baixo nível sócio-econômico e negligência nos cuidados com a saúde.…”
Section: Discussionunclassified
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“…[1][2][3] Cranial base defects resulting from tumors involving the orbit may involve any number of subsites in the anterior cranial base (Zone I) or middle fossa (Zone II). [4][5] Reconstructive techniques for exenteration vary from simple local flaps to complex free flaps, but large defects with involvement of the cranial base are often best addressed with free tissue transfer to minimize complications. 6 Skull base reconstruction requires protection for the central nervous system and creating a watertight dural seal as outlined in detail by Irish et al 1,[4][5] The integrity of this seal is critical to the success of skull base surgery, as it prevents complications such as CSF leak and meningitis, the latter of which is reported in 10-25% of patients in the literature.…”
Section: Introductionmentioning
confidence: 99%