Tumor Heterogeneity Research and Innovation in Biologically Based Radiation Therapy From the National Cancer Institute Radiation Research Program Portfolio

Abstract

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Introducing Specific Iodine Ions in Perovskite‐Based Nanocomplex to Cater for Versatile Biomedical Imaging and Tumor Radiotherapy

“…[1,2] The diversity, complexity, and heterogeneity of this disease impel multimodal biomedical imaging (including optical imaging, radionuclide imaging, and X-ray computed tomography) and imaging-guided therapy to receive more attention, as some cancers have relatively high survival rates if diagnosed in the early stages or treated precisely. [3][4][5][6] As an essential mode DOI: 10.1002/adhm.202302721 of biomedical imaging, optical methods enable the visualization of physiological and pathological processes on a wide spatial scale (from molecule to organism) with high sensitivity using fluorescent agents. [7][8][9] Compared with traditional organic dyes and fluorescent proteins, inorganic nanoparticles (NPs), such as quantum dots, possess many novel unique optical properties, and thus, broaden new appealing opportunities for exploring valuable biological mechanisms.…”

Artificial Intelligence and the future of radiotherapy planning: The Australian radiation therapists prepare to be ready

“…In the fast‐evolving field of radiation oncology, complex solutions are now being developed in order to transition away from a standardised homogenous irradiation approach towards more complex deliveries. 1 This evolution has no doubt been facilitated by the introduction of advanced treatment planning and delivery methodologies based on modulated approaches (such as volumetric modulated arc therapy and intensity modulated radiation therapy). These techniques, allowing the sculpting of doses around organs at risk while also maintaining the required tumour coverage using complex optimisation algorithms, are now commonly used worldwide.…”