Tumor Basal Area and Metastatic Death After Proton Beam Irradiation for Choroidal Melanoma

Proton beam radiotherapy in the management of uveal melanoma: Clinical experience in Scotland

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Proton beam radiotherapy in the management of uveal melanoma: Clinical experience in Scotland

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Proton beam therapy for the treatment of uveal melanoma in Scotland

“…Based on COMS and meta-analysis of studies, the predicted 5-year disease-specific mortality rate was 31–35% for large tumours, 10% for medium tumours and 1% for small tumours 13. Other studies have reported varying 5-year disease-specific survival rates of 75.6–90.0% 2–4 6 7 10. Our patients' survival rate is comparable with other studies, lying towards the upper end of those reported.…”

“…The mean height of all treated tumours was 6.7 mm, and the mean diameter was 15.4 mm. In comparison with other studies, the tumours selected for PBT treatment were towards the upper end of the range in terms of height and diameter 2–4 6 7 10–12…”

Calculated tumour volume as a prognostic parameter for survival in choroidal melanomas

“…Guthoff 16 calculated a biconvex-shaped volume of a sectional area of two sphere segments, Gass 17 and Char et al 7 used the same ellipsoidal formula of p/6  length  width  height to calculate the tumour volume, and thereafter to calculate a tumour growth rate in two different ways and the calculation of Li et al 18 based on a formula with spherical segments using the radius of the eye, largest tumour diameter, perpendicular tumour diameter, and tumour height as calculation parameters.…”

Proton beam radiotherapy in the management of uveal melanoma: Clinical experience in Scotland

“……”

Proton beam therapy for the treatment of uveal melanoma in Scotland

“…Based on COMS and meta-analysis of studies, the predicted 5-year disease-specific mortality rate was 31–35% for large tumours, 10% for medium tumours and 1% for small tumours 13. Other studies have reported varying 5-year disease-specific survival rates of 75.6–90.0% 2–4 6 7 10. Our patients' survival rate is comparable with other studies, lying towards the upper end of those reported.…”

“…The mean height of all treated tumours was 6.7 mm, and the mean diameter was 15.4 mm. In comparison with other studies, the tumours selected for PBT treatment were towards the upper end of the range in terms of height and diameter 2–4 6 7 10–12…”

Calculated tumour volume as a prognostic parameter for survival in choroidal melanomas

“…Guthoff 16 calculated a biconvex-shaped volume of a sectional area of two sphere segments, Gass 17 and Char et al 7 used the same ellipsoidal formula of p/6  length  width  height to calculate the tumour volume, and thereafter to calculate a tumour growth rate in two different ways and the calculation of Li et al 18 based on a formula with spherical segments using the radius of the eye, largest tumour diameter, perpendicular tumour diameter, and tumour height as calculation parameters.…”

Proton beam radiotherapy in the management of uveal melanoma: Clinical experience in Scotland

“……”

Proton beam therapy for the treatment of uveal melanoma in Scotland

“…Based on COMS and meta-analysis of studies, the predicted 5-year disease-specific mortality rate was 31–35% for large tumours, 10% for medium tumours and 1% for small tumours 13. Other studies have reported varying 5-year disease-specific survival rates of 75.6–90.0% 2–4 6 7 10. Our patients' survival rate is comparable with other studies, lying towards the upper end of those reported.…”

“…The mean height of all treated tumours was 6.7 mm, and the mean diameter was 15.4 mm. In comparison with other studies, the tumours selected for PBT treatment were towards the upper end of the range in terms of height and diameter 2–4 6 7 10–12…”

Calculated tumour volume as a prognostic parameter for survival in choroidal melanomas

“…Guthoff 16 calculated a biconvex-shaped volume of a sectional area of two sphere segments, Gass 17 and Char et al 7 used the same ellipsoidal formula of p/6  length  width  height to calculate the tumour volume, and thereafter to calculate a tumour growth rate in two different ways and the calculation of Li et al 18 based on a formula with spherical segments using the radius of the eye, largest tumour diameter, perpendicular tumour diameter, and tumour height as calculation parameters.…”