Tuberculous brain abscess

Rab, Syed M.; Bhatti, Iqtidar H.; Ghani, Abdul Rahman Izaini; Khan, Anjum

doi:10.3171/jns.1975.43.4.0490

Cited by 15 publications

(18 citation statements)

References 13 publications

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“…Pathologically, striking similarity between non‐specific pyogenic abscess and tuberculous abscess has been noted frequently 2,5–7,9,14,15 . Identification of the tubercle bacilli, therefore, is necessary in separating them.…”

Section: Discussionmentioning

confidence: 99%

“…For example, it was asserted that tuberculous abscesses were devoid of the granulomatous reaction relating to tuberculosis 5,7,12 . However, others described or demonstrated granulomas containing epithelioid cells and Langhans’ giant cells in the wall of the tuberculous abscesses 6,8,10,14,16,17,24 . Tyson et al 8 and Connolly believed that tuberculous abscess and tuberculoma were variants of the same pathological process but at different stages of development 36 .…”

Section: Discussionmentioning

confidence: 99%

“…However, they were undoubtedly tuberculous because of the presence of AFB and the absence of caseous necrosis. The remaining 35 instances composed 19 cases of classical tuberculous abscess (54%) 1–5,7,9,12–14,18–22,27,29 and 16 examples of atypical tuberculous abscess (46%) 6,8,10,13–17,19,22,24,25,28,32 …”

Section: Discussionmentioning

confidence: 99%

“…To the best of our knowledge, only 41 acceptable examples were reported in the English language. In 40 of the patients the lesion occurred intracranially, 1–33 while in the remaining one patient it occurred in the spinal cord 34 . Eight of the 41 patients also had the acquired immunodeficiency syndrome (AIDS) 18,19,29,30,32 .…”

Section: Introductionmentioning

confidence: 99%

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Tuberculous brain abscess: A case report with a review of the literature in English

Shuangshoti

1999

Neuropathology

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A 69‐year‐old man had a tuberculous brain abscess in the right frontal lobe as well as an underlying alcoholic cirrhosis of the liver. The abscess responded well to combined surgical excision and antituberculous treatment. A review of 42 patients, including this patient who had tuberculous abscesses of the central nervous system (CNS) disclosed 54% of classical (genuine, true or typical) lesions morphologically similar to the pyogenic abscess, and 46% of atypical lesions having granulomatous changes without caseous necrosis in the abscess wall. The size of the abscesses ranged from 2 mm to 5 cm across. Some abscesses contained 3–60 mL of pus. Most tuberculous abscesses resulted from hematogenous dissemination of tubercle bacilli from primary tuberculous foci outside the CNS; a few were probably related to direct extension of tuberculosis of the ear. Approximately 58% of patients were aged in the first three decades of life and 22% of patients were children of less than 15 years of age. The mean age was 31 years for both genders. The sexual ratio was 7:6 for males and females. The frontal lobe and cerebellum were the common sites of occurrence. Approximately 19% of patients with CNS tuberculous abscesses were associated with the acquired immunodeficiency syndrome (AIDS). Combined surgical extirpation and antituberculous drugs were the treatment of choice. Needle aspiration combined with appropriate antituberculous drugs have yielded satisfactory results in some patients. An intra‐operative smear and a stain of pus for acid‐fast bacilli is necessary for rapidly distinguishing between a tuberculous abscess and a pyogenic abscess as well as for proper immediate postoperative treatment. Geographically, the CNS tuberculous abscesses were scattered in many countries, particularly in India and the USA. Their increased incidence is expected in relation to the present prevalence of AIDS.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Tuberculous brain abscess: A case report with a review of the literature in English

Shuangshoti

1999

Neuropathology

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“…[3,4] Low oxygen levels make liver an inhospitable organ for bacterial growth. [5] Approximately a 100 reported cases are known in literature, to the best of our knowledge.…”

Section: Discussionmentioning

confidence: 99%

Isolated Tubercular Liver Abscess: an entity rarely thought, diagnosed on cytology

Bahadur

Narula

Anand

et al. 2017

APALM

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Intracranial tuberculous abscess mimicking malignant glioma

et al. 1994

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Brain abscess is probably the least common manifestation of tuberculous infection of the central nervous system; meningitis and tuberculoma are much more common. A case of tuberculous brain abscess in a 23-year-old man with previous history of Tbc meningitis is presented. The computerized tomographic scan demonstrated a unilocular space-occupying lesion in the left thalamic region, surrounded by a thick hyperdense enhancing rim. It is suggested that a relatively long clinical history and previous Tbc meningitis history together with the appearance of a thick-walled abscess-like lesion on the CT scan may indicate the diagnosis of a tuberculous brain abscess. Only after neurosurgical removal of the abscess, the pathohistological examination reveal tuberculous etiology of the abscess. The patient later died from aspiration bronchopneumonia. Only 28 instances of tuberculous abscess have been reported in the literature.

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Tuberculous brain abscess

Cited by 15 publications

References 13 publications

Tuberculous brain abscess: A case report with a review of the literature in English

Tuberculous brain abscess: A case report with a review of the literature in English

Isolated Tubercular Liver Abscess: an entity rarely thought, diagnosed on cytology

Intracranial tuberculous abscess mimicking malignant glioma

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