Tuberculoma of the cavernous sinus mimicking a meningioma: Case report and review of the literature

Boutarbouch, Mahjouba; Arkha, Yasser; Gana, R.; Maquili, Moulay Rachid El; Bellakhdar, F.

doi:10.1016/j.jns.2008.11.022

Cited by 21 publications

(17 citation statements)

References 24 publications

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“…The time from primary lung infection to CNS tuberculoma is age- and immune-dependent,[12] and the tuberculoma may lie latent for years with activation from Rich's focus. [5]…”

Section: Discussionmentioning

confidence: 99%

“…[36] Unusual reported locations are the hypothalamic region, Meckel's cave, sellar and suprasellar regions, cerebellopontine angle, and intraventricular spaces. [79111518] Cavernous sinus (CS) tuberculomas are extremely rare, with only eight[245813141623] cases published. Furthermore, isolated CNS tuberculomas without systemic TB, as our case, are exceptional and commonly misdiagnosed.…”

Section: Introductionmentioning

confidence: 99%

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Cavernous sinus tuberculoma mimicking a neoplasm: Case report, literature review, and diagnostic and treatment suggestions for tuberculomas in rare locations

et al. 2013

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Background:Cavernous sinus tuberculomas are extremely rare, but the increasing incidence worldwide of central nervous system (CNS) tuberculosis, mostly due to human immunodeficiency virus and poor sanitary conditions, and the ability of tuberculomas to mimic a brain neoplasm makes cavernous sinus tuberculomas a suspicious pathologic finding in the differential diagnosis of a brain space-occupying lesion.Case Description:We present an immunocompetent patient with no signs of systemic tuberculosis and an isolated right cavernous sinus space-occupying lesion. A skull base approach was performed and tumor resection achieved. The postoperative course was uneventful. Pathologic findings consisted of a tuberculoma and antituberculous treatment was immediately begun with total tumor regression after a 12-month regimen. After reviewing the literature, we propose suggestions to orient the diagnosis and a treatment algorithm for tuberculomas in rare locations.Conclusion:Tuberculomas in rare locations, as the cavernous sinus, are a challenging pathology as they have the ability to mimic a brain neoplasm. Although first line treatment are antituberculous therapy (4 drugs for at least 12 months) and adjuvant steroids, in inconclusive cases, surgical biopsy or excision is recommended for histopathologic confirmation and to reduce the mass effect, always following with antituberculous therapy and adjuvant steroids.

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“…The time from primary lung infection to CNS tuberculoma is age- and immune-dependent,[12] and the tuberculoma may lie latent for years with activation from Rich's focus. [5]…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cavernous sinus tuberculoma mimicking a neoplasm: Case report, literature review, and diagnostic and treatment suggestions for tuberculomas in rare locations

et al. 2013

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“…The incidence of coexistent CNS tuberculoma and tuberculous meningitis is between 10% and 50%. [46] Tuberculomas are primarily located in the cerebral hemisphere, although tuberculomas have been found in the pituitary stalk,[1] sellar and suprasellar regions,[789] corpus callosum,[10] cavernous sinus,[111213] brainstem,[1415161718] cerebellum[1920] and intraventricular. [212223] Intraventricular tuberculomas are rare, and, among them, third ventricular tuberculoma is very rare; only one case has been reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

Third ventricular tuberculoma mimicking as a tumor: Report of a very rare case

Sharma¹,

Kaushal²,

Vaidya³

et al. 2017

Asian J Neurosurg

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Intracranial tuberculoma is a common neurosurgical problem in developing countries; however, intraventricular tuberculoma is a rare entity. Here, we report a rare case of third ventricular tuberculoma in a 21-year-old girl who presented with features of raised intracranial pressure. Radiological findings and management of third ventricular tuberculoma would be discussed and literature regarding such lesions will be reviewed.

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“…When tubercular granulomas occur at unusual sites in the skull base, a conclusive pre-operative diagnosis is difficult to establish, despite advances in neuro-imaging techniques [3,17,18]. This is emphasized by the fact that in nearly all published clinical reports about cavernous sinus TB, patients underwent surgery - either to achieve a definite tissue diagnosis or with an erroneous diagnosis of meningioma [6,7,9,10,13]. …”

Section: Discussionmentioning

confidence: 99%

“…Cavernous sinus tuberculomas are extremely rare, and only 10 cases have been reported in the literature. In all reported instances, the patients were adults [4,5,6,7,8,9,10,11,12,13]. The occurrence of such a lesion in a child and the extensive involvement of the cavernous sinus, Meckel's cave, petrous apex and petroclival region by the granulomatous lesion make this a unique case.…”

Section: Introductionmentioning

confidence: 99%

Tuberculoma of the Cavernous Sinus and Meckel's Cave in a Child

Kumar

Madhugiri

Verma³

et al. 2013

Pediatr Neurosurg

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Tuberculous infection of the cavernous sinus and Meckel's cave is extremely rare. In this report, we describe a patient with tuberculoma of the cavernous sinus and Meckel's cave, extending to the petrous apex. The patient underwent microsurgical excision of the lesion and antitubercular chemotherapy resulting in a good outcome. We describe the diagnostic difficulties and review the relevant literature.

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Tuberculoma of the cavernous sinus mimicking a meningioma: Case report and review of the literature

Cited by 21 publications

References 24 publications

Cavernous sinus tuberculoma mimicking a neoplasm: Case report, literature review, and diagnostic and treatment suggestions for tuberculomas in rare locations

Cavernous sinus tuberculoma mimicking a neoplasm: Case report, literature review, and diagnostic and treatment suggestions for tuberculomas in rare locations

Third ventricular tuberculoma mimicking as a tumor: Report of a very rare case

Tuberculoma of the Cavernous Sinus and Meckel's Cave in a Child

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