Journal of Cell Biology volume 216, issue 2, P379-391 2016 DOI: 10.1083/jcb.201608043 View full text
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Simon D’Archivio, Bill Wickstead

Abstract: The kinetochore complex is conserved across many eukaryotes, but the protozoan lineage Kinetoplastida builds kinetochores from components without apparent homology to models. D’Archivio and Wickstead describe a new family of proteins with homology to outer kinetochore proteins Ndc80 and Nuf2 that defines the outer kinetochore of trypanosomes, suggesting that all eukaryotes have divergent versions of a universal kinetochore machine.