Trousseau syndrome

Maharaj, Satish; Omar, Michael; Seegobin, Karan; Chang, Simone

doi:10.3949/ccjm.87a.19086

Cited by 3 publications

(3 citation statements)

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“…Monitoring the level of D-dimer, which is helpful to evaluate the treatment effects. [1,2] In addition, a retrospective study by Nouh et al [2] suggested the "TTS" (bilateral anterior and posterior circulation acute ischemic diffusion-weighted imaging lesions) as a major contributor to Trousseau syndrome. A evaluation of all presentations of TTS identified 19 different etiologies.…”

Section: Discussionmentioning

confidence: 99%

“…The clinical symptoms of Trousseau syndrome are mostly migratory phlebitis, cerebrovascular accident, myocardial infarction, peripheral arterial occlusion, venous thromboembolism, idiopathic deep vein thrombosis, hepatic veno-occlusive disease, and thrombotic thrombocytopenic purpura, multiple organ dysfunction syndrome, and disseminated intravascular coagulation. [1–3] In this case, the patient developed multiple cerebral infarction, myocardial injury, renal infarction, splenic infarction, and lower extremity arterial thrombosis, and finally was diagnosed Trousseau syndrome. Combined with the literature, the specific abnormal laboratory marker was the elevation of the D-D polymers, not only provide a basis for treatment, but also a key indicator of diagnosis.…”

Section: Introductionmentioning

confidence: 96%

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A case report of Trousseau syndrome

Liu,

Zhang

2023

Medicine

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Rationale: In 1865, Trousseau first discovered pulmonary embolism caused by multiple venous thrombosis in patients with gastric cancer, and later all clinical manifestations of malignant patients during pathogenesis due to abnormal coagulation and fibrinolysis were referred to collectively as Trousseau syndrome. Trousseau syndrome is not a benign thrombophlebitis, and when diagnosed it requires immediate treatment. The survival rate over 1 year is only 12%. Stroke in cancer patients has distinct characteristics different from conventional stroke and has higher mortality. Patient concerns: A 54-year-old female presented to the Department of Otolaryngology with recurrent right nasal bleeding for 4 days. After surgery, the patient experienced 7 different cerebral infarction courses. Finally died of brain herniation. Diagnosis: The specific abnormal laboratory index is the increase of D-dimer, suggesting the hypercoagulation state. The patient developed multiple cerebral infarction, myocardial injury, renal infarction, splenic infarction, and lower extremity arterial thrombosis, and finally was diagnosed Trousseau syndrome. Interventions: In the treatment, aspirin and atorvastatin were selected, but it did not work very well. D-dimer were high, we used low molecular weight heparin, and D-dimer decreased significantly. Outcomes: Finally the patient died of brain herniation. Conclusion: The raise of D-dimer and typical magnetic resonance imaging manifestation which provides a greater basis for diagnosis. The specific abnormal laboratory index is the increase of D-dimer, which provides direction for treatment and helps to evaluate treatment effect.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

A case report of Trousseau syndrome

Liu,

Zhang

2023

Medicine

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“…A more appropriate designation is "cancer-associated thrombosis" and disease entities found in this condition, as noted by Dr. Maharaj and colleagues. 5…”

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confidence: 99%

Trousseau sign and syndrome: Erroneous terms

Yale

Tekiner

Mazza

et al. 2020

CCJM

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A case of Trousseau syndrome: Screening, detection and complication

Liu,

Jiang,

et al. 2024

Open Life Sciences

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Trousseau syndrome (TS) is a malignant tumor-mediated complication of the hypercoagulable state with an unknown etiology. Laboratory testing results in patients with TS have indicated elevated D-dimer levels. The imaging analysis in patients who had undergone stroke has shown the presence of several cerebral infarction lesions in multiple regions. Since patients have had malignant tumors for a long time when they suffer from a secondary stroke, the optimum time for radical tumor treatment is usually missed. This study reports a case to improve the early screening and detection of TS and reduce the risk of recurrence of cerebral infarction.

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Trousseau syndrome

Cited by 3 publications

References 0 publications

A case report of Trousseau syndrome

A case report of Trousseau syndrome

Trousseau sign and syndrome: Erroneous terms

A case of Trousseau syndrome: Screening, detection and complication

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