Tropical Pulmonary Eosinophilia- An Elaborate Case Series

Utpat, Ketaki Vasudeo; Sanghavi, Parang; Desai, Unnati Deepakkumar; Jankharia, Bhavin; Joshi, Jyotsna M

doi:10.18410/jebmh/2019/100

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“…Most patients show marked symptomatic, functional, and radiographic improvement after three weeks [ 2 ]. The analysis of a case series showed that response in laboratory and lung function parameters following treatment was variable [ 12 ]. An incomplete response results from persistent low-grade inflammation that leads to interstitial fibrosis and chronic respiratory insufficiency.…”

Section: Discussionmentioning

confidence: 99%

A Case of Tropical Pulmonary Eosinophilia With Incomplete Response to Diethylcarbamazine Therapy

Datta¹,

Chhotray²,

Jena³

et al. 2023

Cureus

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Tropical pulmonary eosinophilia (TPE) is a specific pulmonary manifestation of lymphatic filariasis. There is overwhelming infiltration of eosinophils in the lung parenchyma in response to microfilaria. The characteristic features include paroxysmal respiratory symptoms, strikingly high blood eosinophil count, elevated level of immunoglobulin (Ig) E along with high titer of anti-filarial antibody. Treatment with diethylcarbamazine (DEC) has an excellent favorable response. However, recovery may often be incomplete.We present a case of a 36-year-old man with TPE who had complete symptomatic improvement after a three-week course of DEC, but only a partial response in radiological and pulmonary function abnormalities.

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Section: Discussionmentioning

confidence: 99%