Triterpenoid saponins from Sophora subprostrata

Sakamoto, Shiho; Kuroyanagi, Masanori; Ueno, Akihiko; Sekita, Setsuko

doi:10.1016/0031-9422(92)80286-n

Cited by 19 publications

(8 citation statements)

References 6 publications

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“…Soyasaponin II methyl ester was previously isolated from Sophora subprostrata 5 and Astragalus sinicus. 6 The structure was determined on the basis of FAB-MS, 1 H and 13 C NMR spectral and chemical evidences, and its proton and carbon signals were assigned just by comparing the NMR data to those of the related compounds with similar structures.…”

Section: Resultsmentioning

confidence: 99%

Structural determination of saponins from Hedysarum polybotrys

Liu

Zhang

Chen

et al. 2006

Magnetic Reson in Chemistry

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Four saponins (1-4) were isolated from the roots of Hedysarum polybotrys Hand.-Mazz. and obtained from Hedysarum (Tourn.) L for the first time. Their structures were identified on the basis of spectroscopic data. MS, 1D and 2D NMR including HMQC, HMBC, 1H-1H COSY and NOESY permitted correct assignments of all 1H and 13C signals of 1 and 2, and the 13C NMR data of 2 were reported for the first time.

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Section: Resultsmentioning

confidence: 99%

Structural determination of saponins from Hedysarum polybotrys

Liu

Zhang

Chen

et al. 2006

Magnetic Reson in Chemistry

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“…subprostrata is a traditional Chinese medicinal plant. Its roots are used as an antipyretic, antidote, analgesic, it has been reported to have antitumour activity (Chen & Jiang, 1994), the roots of S. subprostrate have been used as a Korean traditional medicine for the treatment of fever, inflammation, peptic ulcer, cancer and reported that antitumour activity is to be the result of cytotoxicity of its alkaloids (Sakamoto et al, 1992;Zheng et al, 1997).…”

Section: Ethnopharmacological Usementioning

confidence: 99%

“…It has been known to contain flavonoids, alkaloids, saponins, phenols and lignins. The antitumor activity of S. subprostrata crude preparation has been reported and theorized to be the result of cytotoxicity of its alkaloids (Sakamoto et al, 1992;Zheng et al, 1997).…”

Section: Ethnopharmacological Usementioning

confidence: 99%

A review on phytochemical, ethnomedical and pharmacological studies on genus Sophora, Fabaceae

Krishna¹,

Knv²,

Sandhya³

et al. 2012

Rev. bras. farmacogn.

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Sophora is a genus of the Fabaceae family, contains about 52 species, nineteen varieties, and seven forms that are widely distributed in Asia, Oceanica, and the Pacific islands, in the family Fabaceae of herbaceous (Sophora flavescens Aiton) to trees (Sophora japonica L.). More than fifteen species in this genus have a long history of use in traditional Chinese medicines. In the last decades the use of this genus in traditional Chinese drugs has led to rapid increase in the information available on active components and reported to posses various pharmacological/ therapeutic properties. The paper reviews the ethnopharmacology, the biological activities and the correlated chemical compounds of genus Sophora, Fabaceae. More than 300 compounds has been isolated, among them major are quinolizidine alkaloids particularly matrine and oxymatrine and flavonoids particularly prenylated and isoprenylated flavonoids. Modern pharmacological studies and clinical studies demonstrated that these chemical constituens possess wide reaching pharmacological actions like anti oxidant, anticancer, anti-asthamatic, anti-neoplastic, antimicrobial, antiviral, antidote, anti pyretic, cardiotonic, antinflammatory, diuretic and in the treatment of skin diseases like eczema, colitis and psoriasis.

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“…Peaks 3 and 4 presented the fragment ion m/z 489 [Agly − H] − were tentatively identified as derivatives of kudzusapogenol A, a penta-oxygenated oleanane triterpene with oxygenations at C-21 and C-22, the oxygenation at C-29 is supported by the loss of 32 Da (methanol) observed in the fragment ion m/z 457 [Agly − H − CH 4 O] − . Compound 3 was putatively identified as Pen-HexA-kudzusapogenol A and compound 4 as subproside II, a saponin isolated from Sophorae subprostrata (Leguminosae) [36,43].…”

Section: Resultsmentioning

confidence: 99%

Rapid Characterization of Triterpene Saponins from Zornia brasiliensis by HPLC-ESI-MS/MS

et al. 2019

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Zornia brasiliensis Vogel (Leguminosae) is a species popularly known in Brazil as “urinária”, “urinana”, and “carrapicho”, it is popularly used as a diuretic and in the treatment of venereal diseases. A specific methodology to obtain a saponin-enriched fraction and high-performance liquid chromatography coupled with diode array detection, ion trap mass spectrometry, and TOF-MS (HPLC-DAD-ESI-MS/MS) was applied for the analysis of triterpene saponins. The MS and MS/MS experiments were carried out by ionization in negative mode. Molecular mass and fragmentation data were used to support the structural characterization of the saponins. Based on retention times, high-resolution mass determination and fragmentation, 35 oleanane-triterpene saponins were tentatively identified in Z. brasiliensis.

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Triterpenoid saponins from Sophora subprostrata

Cited by 19 publications

References 6 publications

Structural determination of saponins from Hedysarum polybotrys

Structural determination of saponins from Hedysarum polybotrys

A review on phytochemical, ethnomedical and pharmacological studies on genus Sophora, Fabaceae

Rapid Characterization of Triterpene Saponins from Zornia brasiliensis by HPLC-ESI-MS/MS

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