volume 35, issue 2, P1113-1124 2020
DOI: 10.1002/ptr.6892
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Abstract: Trigonelline, a major alkaloid component of fenugreek, has been demonstrated to have several biological activities, including antidiabetic and anticancer effects. This study aimed to examine the possible application of trigonelline as an anti‐obesity compound based on an investigation of its enhancement of lipid catabolism and induction of browning in white adipocytes. Trigonelline induces browning of 3T3‐L1 white adipocytes by enhancing the expressions of brown‐fat signature proteins and genes as well as beig…

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