Trichilemmal carcinoma: a case report of a rare skin cancer occurring in a renal transplant patient

Garrett, Algin B.; Scott, Kimberly A.

doi:10.1097/01.tp.0000074317.77586.ba

Cited by 15 publications

(12 citation statements)

References 4 publications

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“…1 Histologically, the tumor is purely intraepithelial or is more commonly associated with an invasive component centered around the pilosebaceous unit, which may reach from the epidermis to subcutaneous fat. 2 They are frequently continuous with the epidermis and the follicular epithelium. 4 When large, they have hemorrhage and/or necrosis focuses.…”

Section: Discussionmentioning

confidence: 99%

“…5,10 The treatment recommended in the literature is micrographic Mohs surgery, as it does not show recurrence signs even after many years of treatment. 2,3,4,6 The trichilemmal carcinoma generally has good prognosis and reports of deep invasion and local recurrence cases are uncommon. The present study shows a recurrent trichilemmal carcinoma case of difficult treatment, which presented on the same location where a basal-cell carcinoma had been previously treated with surgery and radiotherapy.…”

Section: Discussionmentioning

confidence: 99%

“…As a rule, it appears as a solitary lesion after the fifth decade of life. 2 The diagnosis is established by means of histopathological examination using hematoxylin-eosin staining which, when necessary, is complemented by immunohistochemistry of the lesion. The treatment may be Mohs' technique or simple lesion excision.…”

Section: Introductionmentioning

confidence: 99%

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Carcinoma triquilemal: relato de caso

Roismann¹,

Freitas²,

Ribeiro

et al. 2011

An. Bras. Dermatol.

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Abstract:The trichilemmal carcinoma is a rare tumor that usually occurs on sun-exposed skin, especially on the face, scalp, neck and back of hands, mainly in elderly subjects but commonly between the 4th and 9th decades of life. It is not a gender-based illness. This study shows a difficult to treat case of recurrent trichilemmal carcinoma on the same location of a basal-cell carcinoma previously treated with surgery and radiotherapy. Keywords: Neoplasms, adnexal and skin appendage; Neoplasms, radiation-induced; Skin neoplasms Resumo: O carcinoma triquilemal é um tumor raro, que ocorre, geralmente, na pele exposta ao sol, principalmente face, couro cabeludo, pescoço e dorso das mãos, em indivíduos idosos, entre a 4ª e 9ª décadas de vida, sem predilação por sexo. O presente estudo mostra um caso de carcinoma triquilemal, recidivado, de difícil tratamento, em mesma topografia de um carcinoma basocelular tratado previamente com cirurgia e radioterapia. Palavras-chave: Neoplasias cutâneas; Neoplasias induzidas por radiação; Neoplasias de anexos e de apêndices cutâneos

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Carcinoma triquilemal: relato de caso

Roismann¹,

Freitas²,

Ribeiro

et al. 2011

An. Bras. Dermatol.

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“…7 To our knowledge, TLCA in OTRs has been reported only twice. 3,8 The case diagnosed as "malignant proliferating trichilemmal tumor" in another renal transplant recipient 9 seems to correspond to a malignant proliferating trichilemmal cyst (also known as malignant/proliferating pilar tumor) of the scalp; this is a histogenetically related tumor deriving from the outer root sheath of the hair follicle, but shows different clinicopathologic features. However, the true incidence of TLCA may be underestimated because this tumor may be pathologically misdiagnosed as clear-cell squamous (or basal) cell carcinoma, sebaceous carcinoma or clear-cell Bowen's disease.…”

Section: Discussionmentioning

confidence: 98%

Trichilemmal Carcinoma of the Skin Mimicking a Keloid in a Heart Transplant Recipient

Kanitakis

Euvrard

Sebbag

et al. 2007

The Journal of Heart and Lung Transplantation

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“…This rare cutaneous cancer usually occurs on the sun-exposed areas of the elderly, 1 although it can appear as multiple lesions on non-sun-exposed skin. 2 Clinically, it may be mistaken for squamous cell carcinoma, basal cell carcinoma, nodular melanoma, or keratoacanthoma. It has been shown to be a malignant form of a trichilemmoma.…”

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confidence: 98%

Multiple Recurrence of Trichilemmal Carcinoma of the Scalp in a Young Adult

Külahçi¹,

Öksüz²,

Küçükodacı

et al. 2010

Dermatologic Surgery

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The authors have indicated no significant interest with commercial supporters.T richilemmal carcinoma is a rare, cutaneous adnexal malignant tumor deriving from the outer root sheath of hair follicles. This rare cutaneous cancer usually occurs on the sun-exposed areas of the elderly, 1 although it can appear as multiple lesions on non-sun-exposed skin. 2 Clinically, it may be mistaken for squamous cell carcinoma, basal cell carcinoma, nodular melanoma, or keratoacanthoma. It has been shown to be a malignant form of a trichilemmoma. 3 Trichilemmal carcinoma generally has a nonaggressive course. Boscaino and colleagues reported that, after excision of the lesions in seven patients, there was no recurrence of the tumor within a 2-month to 4-year follow-up. 1 Trichilemmal carcinoma poorly mimics differential squamous cell carcinoma, and its biological behavior is unpredictable because it rarely can produce distant metastasis. 4 Most of the time there is a unique lesion that presents a papulonodular aspect with possible keratosis or ulceration on the top of it. Simple excision with adequate safety margin is a safe, low-cost, effective mode of treatment. 5 The appropriate treatment also includes wide resection and postoperative follow-up of the patient to facilitate early diagnosis of the recurrence and distant metastasis. 4The clinical behavior of the trichilemmal carcinoma appears to be relatively indolent, despite its cytologically malignant appearance. Local recurrence after wide excision is rare, and metastasis has not been reported. 6 It typically manifests as a single, superficial nodule measuring less than 2 cm that commonly undergoes ulceration. 7 We present here a case of local recurrence of trichilemmal carcinoma three times after excision. Case ReportWe describe the case of a 20-year-old white man who, as of 2008, had a 5-year history of a persistent lesion on his scalp and had been operated twice for this tumor before referral to our center. The first and second operations were performed 2 years and 6 months, respectively, before the referral. He had no pathologic research report of the first excision material. The second excision material, which was taken 6 months before application to our center, was reported as trichilemmal carcinoma with involvement of the margins of resection. Upon being examined at our center, he was found to have a solitary subcutaneous exophytic, hyperkeratotic, indurated papulonodular, 3-cm-wide lesion without erythema and ulceration. He had no lymphadenopathy and no history of any other tumor or long-time sun exposure. At his first application to our center, wide surgical tumor excision and reconstruction with rotation flap was performed. The pathology result was reported as malignant trichilemmal carcinoma with tumor-free margins.

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Trichilemmal carcinoma: a case report of a rare skin cancer occurring in a renal transplant patient

Cited by 15 publications

References 4 publications

Carcinoma triquilemal: relato de caso

Carcinoma triquilemal: relato de caso

Trichilemmal Carcinoma of the Skin Mimicking a Keloid in a Heart Transplant Recipient

Multiple Recurrence of Trichilemmal Carcinoma of the Scalp in a Young Adult

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