Triazole-based Zn2+-specific molecular marker for fluorescence bioimaging

Sinha, Sougata; Mukherjee, Trinetra; Mathew, Jomon; Mukhopadhyay, Subhra Kanti; Ghosh, Subrata

doi:10.1016/j.aca.2014.03.002

Cited by 37 publications

(12 citation statements)

References 67 publications

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“…5a, Al 3+ caused the change of fluorescence enhancement. However, Al 3+ is a nonessential element for living systems, human body naturally contains only 35 mg Al 3+ (about 0.7 ppm; while Zn 2+ about 60 ppm) [33,34]. It suggested that, in common bio-system, Al 3+ cannot cause obvious effect on the detection of Zn 2+ .…”

Section: The Establishment Of Fluorescence Probe Based On Fretmentioning

confidence: 97%

Fluorescent carbon dots for sensitive determination and intracellular imaging of zinc(II) ion

Yang

Kong

et al. 2015

Microchim Acta

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We describe the preparation of carbon dots (CDs) from glucose that possess high stability, a quantum yield of 0.32, and low toxicity (according to an MTT assay). They were used, in combination with the fluorogenic zinc(II) probe quercetin to establish a fluorescence resonance energy transfer (FRET) system for the determination of Zn(II). The CDs are acting as the donor, and the quercetin-Zn(II) complex as the acceptor. This is possible because of the strong overlap between the fluorescence spectrum of CDs and the absorption spectrum of the complex. The method enables Zn(II) to be determined in the 2 to 100 μM concentration range, with a 2 μM detection limit. The method was applied to image the distribution of Zn(II) ions in HeLa cells.

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Section: The Establishment Of Fluorescence Probe Based On Fretmentioning

confidence: 97%

Fluorescent carbon dots for sensitive determination and intracellular imaging of zinc(II) ion

Yang

Kong

et al. 2015

Microchim Acta

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“…Furthermore, Zinpyr-1 is not expected to present a challenge to membrane permeability, because of its structural similarity to the membrane-permeable heavy metal chelator N , N , N ′ , N ′ -tetra(2-picolyl)ethylenediamine (TPEN). Zinpyr-1 has been shown to be loaded in Cos-7 cells where it responds to changes in Zn 2+ concentration [ 66 , 67 ].…”

Section: Zn 2+ Selective Fluorescent Molecular mentioning

confidence: 99%

Development of Functional Fluorescent Molecular Probes for the Detection of Biological Substances

Suzuki

Yokoyama

2015

Biosensors

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This review is confined to sensors that use fluorescence to transmit biochemical information. Fluorescence is, by far, the most frequently exploited phenomenon for chemical sensors and biosensors. Parameters that define the application of such sensors include intensity, decay time, anisotropy, quenching efficiency, and luminescence energy transfer. To achieve selective (bio)molecular recognition based on these fluorescence phenomena, various fluorescent elements such as small organic molecules, enzymes, antibodies, and oligonucleotides have been designed and synthesized over the past decades. This review describes the immense variety of fluorescent probes that have been designed for the recognitions of ions, small and large molecules, and their biological applications in terms of intracellular fluorescent imaging techniques.

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“…[ 19–23 ] So far, many fluorescent sensors based on various fluorescent groups such as fluorophores rhodamine, [ 24,25 ] quinoline, [ 26–30 ] coumarins, [ 31,32 ] heptamethine cyanine, [ 33 ] anthracene, [ 34 ] and others units have been reported for the detection of Zn 2+ . [ 35–41 ] Due to the concentration of Zn 2+ in living things that is about 1.96 × 10 −6 mol L −1 and the World Health Organization (WHO) regulates the concentration of Zn 2+ in drinking water to be 7.0 × 10 −6 mol L −1 , [ 42,43 ] it is still crucial to construct a highly sensitive and selective new fluorescent sensor for the detection of Zn 2+ .…”

Section: Introductionmentioning

confidence: 99%

A novel diarylethene‐based fluorescence sensor with a benzohydrazide unit for the detection of Zn²⁺

Qiu

Cui

et al. 2020

J of Physical Organic Chem

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A novel fluorescent sensor on the basis of diarylethene and benzohydrazide unit was successfully synthesized. Its photochromic and fluorescent switching properties have been studied in detail by the irradiation of UV‐visible (UV‐Vis) lights and the stimulus of Zn2+/EDTA. The sensor exhibited high sensitivity and selectivity toward Zn2+ in tetrahydrofuran, which is not interfered by other cations, especially of congener Cd2+. The fluorescence intensity enhanced 84 times along with a 44‐nm blue shift of the emission peak after adding Zn2+. The stoichiometric ratio between the sensor and Zn2+ was 1:1, and the limit of detection (LOD) was calculated as 5.60 × 10−9 mol L−1. Besides, the sensor was applied in the detection of practical water samples with high accuracy.

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Triazole-based Zn2+-specific molecular marker for fluorescence bioimaging

Cited by 37 publications

References 67 publications

Fluorescent carbon dots for sensitive determination and intracellular imaging of zinc(II) ion

Fluorescent carbon dots for sensitive determination and intracellular imaging of zinc(II) ion

Development of Functional Fluorescent Molecular Probes for the Detection of Biological Substances

A novel diarylethene‐based fluorescence sensor with a benzohydrazide unit for the detection of Zn²⁺

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Triazole-based Zn2+-specific molecular marker for fluorescence bioimaging

Cited by 37 publications

References 67 publications

Fluorescent carbon dots for sensitive determination and intracellular imaging of zinc(II) ion

Fluorescent carbon dots for sensitive determination and intracellular imaging of zinc(II) ion

Development of Functional Fluorescent Molecular Probes for the Detection of Biological Substances

A novel diarylethene‐based fluorescence sensor with a benzohydrazide unit for the detection of Zn2+

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A novel diarylethene‐based fluorescence sensor with a benzohydrazide unit for the detection of Zn²⁺