Trends of Incidence, Clinical Presentation, and In-Hospital Mortality Among Women With Acute Myocardial Infarction With or Without Spontaneous Coronary Artery Dissection

Mahmoud, Ahmed N.; Taduru, Siva Sagar; Mentias, Amgad; Mahtta, Dhruv; Barakat, Amr F.; Saad, Marwan; Elgendy, Islam Y.; Mojadidi, Mohammad K.; Omer, Mohamed; Abu‐Zaid, Ahmed; Agarwal, Nayan; Anderson, R. David; Saw, Jacqueline

doi:10.1016/j.jcin.2017.08.016

Cited by 103 publications

(79 citation statements)

References 29 publications

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“…However, a strong suspicion should be raised in young women presenting with MI as close to 25% of women <50 years old with MI have SCAD on angiography. 15 Although the prevalence of SCAD has been estimated to be between 0.07% and 1.1% of all coronary angiographies performed, 3,16 the exact prevalence is unknown as SCAD can be difficult to diagnose secondary to dissections that may mimic atherosclerotic plaque. Intracoronary imaging, which includes intravascular ultrasound and optical coherence tomography, has aided the accurate diagnosis of SCAD at the expense of an increased risk of extending the dissection.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Coronary Artery Dissection and Its Association With Fibromuscular Dysplasia and Other Vascular Abnormalities

McNair

Parker

Taylor

et al. 2020

The American Journal of Cardiology

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Section: Discussionmentioning

confidence: 99%

Spontaneous Coronary Artery Dissection and Its Association With Fibromuscular Dysplasia and Other Vascular Abnormalities

McNair

Parker

Taylor

et al. 2020

The American Journal of Cardiology

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“…The NIS was developed for the Health Care Cost and Utilization Project (HCUP) [11]. The NIS has been validated internally and externally [12,13]. It has been used previously for describing trends and outcomes of various diseases [14,15].…”

Section: Methodsmentioning

confidence: 99%

Comparative Outcomes of Transapical Versus Transfemoral Access for Transcatheter Aortic Valve Replacement in Diabetics

et al. 2019

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“…SCAD is a rare cause of ACS, but 90% of the cases are reported in women (table 2). 28 In large registries, SCAD is reported as the cause of acute myocardial infarction (AMI) in 1% of cases 29. This is most probably underestimated due to the diagnosis done by standard coronary angiography which cannot detect the dissection if it is only present as intramural haematoma occluding the lumen in the absence of dye fixation typical of intimal tear.…”

Section: Coronary Artery Disease: Spontaneous Coronary Artery Dissectionmentioning

confidence: 99%

Coronary artery disease and acute coronary syndrome in women

Mehilli

Presbitero²

2020

Heart

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There are important dissimilarities in clinical presentation, aggregation of comorbidities, cardiovascular risk factors and the quality of delivery of medical care among men and women with acute coronary syndrome (ACS). Compared with men, despite the well-known older age and more pronounced frailty, women with ACS present later from symptom onset and are at high bleeding risk after invasive procedures. In addition, autoimmune/inflammatory disease, fibromuscular dysplasia, polycystic ovary, early menopause and history of pre-eclampsia are risk factors preceding ACS among younger women. They more often experience myocardial infarction in the absence of obstructive coronary arteries (MINOCA), which makes diagnosis and treatment of ACS among women more challenging compared with men. Women and men do both benefit from guideline-recommended treatment, although, compared with men, women with ACS have a higher adjusted risk of early death, which equalises between both sexes within the first year. Young women with ACS suffer frequently of depression and present often with MINOCA. Compared with young men, they (young women) have a higher risk of death. Therefore, focusing on young patients with ACS, understanding the particular physiopathology of MINOCA and developing programmes targeting comorbidities and depression-related behavioural risk factors are urgently needed.

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Trends of Incidence, Clinical Presentation, and In-Hospital Mortality Among Women With Acute Myocardial Infarction With or Without Spontaneous Coronary Artery Dissection

Abstract: Women presenting with AMI and SCAD appear to be at higher risk of in-hospital mortality. Lower rates of PCI were associated with improved survival, with evidence of worse outcomes when PCI was performed for SCAD in the setting of non with ST-segment elevation myocardial infarction.

Cited by 103 publications

References 29 publications

Spontaneous Coronary Artery Dissection and Its Association With Fibromuscular Dysplasia and Other Vascular Abnormalities

Spontaneous Coronary Artery Dissection and Its Association With Fibromuscular Dysplasia and Other Vascular Abnormalities

Comparative Outcomes of Transapical Versus Transfemoral Access for Transcatheter Aortic Valve Replacement in Diabetics

Coronary artery disease and acute coronary syndrome in women

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