Trends in pulmonary embolism morbidity and mortality in Australia

Shiraev, Timothy; Omari, Abdullah; Rushworth, R. Louise

doi:10.1016/j.thromres.2013.04.032

Cited by 64 publications

(69 citation statements)

References 40 publications

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“…In a study conducted in USA, the mortality rate was reported to decrease from 7.1% to 3.2% over 20 years [1]. In another study conducted in Australia, it was revealed that the mortality rate decreased over years but that PTE was still an important cause of mortality and morbidity in females and the elderly population [4]. In our study, the overall mortality rate was around 13%, and no change was observed in the mortality rate over the years.…”

Section: Discussioncontrasting

confidence: 43%

Does the Incidence and Mortality of Pulmonary Thromboembolism Change Over the Years?

Özsu¹,

Durmuş²,

Coşkuner³

et al. 2017

Turk Thorac J

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OBJECTIVES:In the last 20 years, with the use of computed tomography (CT) angiography, the number of patients diagnosed with pulmonary thromboembolism (PTE) has increased. At the same time, data show that pulmonary embolism mortality has also reduced in this duration. MATERIAL AND METHODS:In this study, we analyzed records of patients with PTE (using ICD's) in the hospital automation system from 2001 to 2013. Data regarding age, sex, date of diagnosis, diagnosis of cancer, hemodynamic status, initial and maintenance treatment, hospital length of stay, and hospital mortality were recorded. Primary endpoints of the study were hospital length of stay and all-cause hospital mortality. RESULTS:The total number of patients included in the study was 1185. The median age was 61 years in 2001 and 71 years in 2013. The number of patients who were diagnosed using CT increased from 10% to 92.8%. Between 2001 and 2013, the number of patients diagnosed with PTE increased, and of all patients with PTE, 13.7% was diagnosed in 2009. The hospital length of stay of 13 days declined to 9 days. The use of a vena cava filter in 2007 was 1.1% and that in 2013 was 4.6%. Mortality rate was 15%, however hospital mortality did not significantly differ over the years but varied between 9.4% and 18.8%. Increased use of thrombolytics in patients with massive PTE has been observed over the years. Massive PTE ratio in 2006 was 8.5% and thrombolytic use was 5.8%, however in 2013, these ratios were 2.6%, 6% respectively (p=0.017). CONCLUSION:Finally, despite the increased number of patients diagnosed with PTE over the years, the mortality rate was not observed to have changed from 2001 to 2013. KEYWORDS:Pulmonary thromboembolism, heparin, thrombolytic, mortality, incidence INTRODUCTIONPulmonary thromboembolism (PTE) is an important public health concern that causes mortality and morbidity. Its non-specific symptoms and findings lead to difficulties in confirming its diagnosis. However, with the use of computed tomography (CT) angiography in recent years, an important step has been taken in the diagnosis of PTE. Moreover, improvements, such as the development of new anticoagulants and mechanical interventions, have occurred in the treatment of PTE. In parallel with all these improvements, data on the incidence and outcomes of the disease seems to be restricted.In a study conducted in USA the incidence of PTE was reported to increase from 23/100,000 to 65/100,000 [1]. On the other hand, in a study conducted in Canada, no significant change was observed in the incidence of PTE in the last decade [2]. A study was conducted on 60853 patients in Italy, and an increase was found in the incidence of PTE in the last 10 years [3]. In our study, the data of patients diagnosed with PTE between 2001 and 2013 were obtained from hospital recordings and were analyzed. MATERIAL AND METHODSIn our study, the records of patients diagnosed with PTE between 2001 and 2013 were obtained from the hospital's automations system (with the International Classification of Di...

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Section: Discussioncontrasting

confidence: 43%

Does the Incidence and Mortality of Pulmonary Thromboembolism Change Over the Years?

Özsu¹,

Durmuş²,

Coşkuner³

et al. 2017

Turk Thorac J

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“…The exact reasons for the discrepancy between the increase in hospital admission rates and the decrease in pulmonary embolism mortality over time are unknown and may warrant further investigation. However, possible explanations have been proposed, including a greater awareness of the incidence of pulmonary embolism in hospitalised patients, an improvement in diagnostic techniques for the identification of this disease [6], more effective treatment, and fewer complications [24]. In this regard, we found a significant increase in the use of CTPA over time, which is associated with an increased incidence of pulmonary embolism and a lower mortality.…”

Section: Discussionmentioning

confidence: 64%

“…Other causes have been suggested to explain the divergence between hospital admission rates and pulmonary embolism mortality, such as preventive health interventions, improved clinical awareness of pulmonary embolism risk, improved diagnosis and treatment of venous thromboembolism, and increased use of thromboprophylaxis [6]. However, a decrease in the prevalence of venous thromboembolism risk factors should have led to a parallel reduction in pulmonary embolism hospital admissions rates [27,28].…”

Section: Pulmonary Vascular Diseases | J De Miguel-díez Et Almentioning

confidence: 99%

“…WIENER et al [4] found an increased incidence, minimal changes in mortality and a substantially lower case fatality rate. Hospital admission rates for pulmonary embolism have also increased over time in the UK [5] and Australia [6]. During recent years, pulmonary embolism mortality has also decreased in these countries [5,6].…”

Section: Introductionmentioning

confidence: 99%

“…Hospital admission rates for pulmonary embolism have also increased over time in the UK [5] and Australia [6]. During recent years, pulmonary embolism mortality has also decreased in these countries [5,6]. Meanwhile, in other countries, such as China, the incidence of pulmonary embolism has remained relatively stable in recent years while the case fatality rate has declined over the same period [7].…”

Section: Introductionmentioning

confidence: 99%

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Trends in hospital admissions for pulmonary embolism in Spain from 2002 to 2011

et al. 2014

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Trends in Mortality Due to Myocardial Infarction, Stroke, and Pulmonary Embolism in Patients Receiving Dialysis

et al. 2022

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IMPORTANCE During the past decades, improvements in the prevention and management of myocardial infarction, stroke, and pulmonary embolism have led to a decline in cardiovascular mortality in the general population. However, it is unknown whether patients receiving dialysis have also benefited from these improvements. OBJECTIVE To assess the mortality rates for myocardial infarction, stroke, and pulmonary embolism in a large cohort of European patients receiving dialysis compared with the general population. DESIGN, SETTING, AND PARTICIPANTSIn this cohort study, adult patients who started dialysis between 1998 and 2015 from 11 European countries providing data to the European Renal Association Registry were and followed up for 3 years. Data were analyzed from September 2020 to February 2022. EXPOSURES Start of dialysis. MAIN OUTCOMES AND MEASURESThe age-and sex-standardized mortality rate ratios (SMRs) with 95% CIs were calculated by dividing the mortality rates in patients receiving dialysis by the mortality rates in the general population for 3 equal periods (1998-2003, 2004-2009, and 2010-2015). RESULTSIn total, 220 467 patients receiving dialysis were included in the study. Their median (IQR) age was 68.2 (56.5-76.4) years, and 82 068 patients (37.2%) were female. During follow-up, 83 912 patients died, of whom 7662 (9.1%) died because of myocardial infarction, 5030 (6.0%) died because of stroke, and 435 (0.5%) died because of pulmonary embolism. Between the periods 1998

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Trends in pulmonary embolism morbidity and mortality in Australia

Cited by 64 publications

References 40 publications

Does the Incidence and Mortality of Pulmonary Thromboembolism Change Over the Years?

Does the Incidence and Mortality of Pulmonary Thromboembolism Change Over the Years?

Trends in hospital admissions for pulmonary embolism in Spain from 2002 to 2011

Trends in Mortality Due to Myocardial Infarction, Stroke, and Pulmonary Embolism in Patients Receiving Dialysis

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