Treatment of squamous cell carcinoma of the skin

Squamous Cell Carcinoma of the Hand

“…24 Honeycutt et al retrospectively compared the same treatments in 484 patients with SCC and found 4-year recurrence rates of 1.1% with EDC, 13% with surgical excision, and 0% with XRT. 25 This study also specifically showed a 4-year recurrence rate of 4% for patients with hand SCC treated with EDC. Cryosurgery has also been advocated for less aggressive lesions.…”

BritishAssociation ofDermatologists' guidelines for the management of squamous cell carcinomain situ(Bowen's disease) 2014

“…64 Studies using curettage and cautery give a wide range of cure rates, with larger series suggesting a recurrence rate of 20%, but they often lack details of treatment regimens and equipment used. 3,31 High cure rates can be achieved; one study showed a recurrence rate of 2% (one out of 52) over 4 years, 65 while another study reported a recurrence rate of 10% (eight of 83) after a follow-up of 2 years. 66 These smaller studies have shown recurrence rates similar or superior to excision.…”

Non-melanoma Skin Cancer in Canada Chapter 5: Management of Squamous Cell Carcinoma

“…38 Cure rates for SCC in situ following ED&C are 93% to 98%. 59,60 In the older literature, ED&C has been associated with 96% to 99% 5-year cure rates in patients with primary low-risk cutaneous SCC. 3,60,61 Recently, this approach has been criticized.…”

“…59,60 In the older literature, ED&C has been associated with 96% to 99% 5-year cure rates in patients with primary low-risk cutaneous SCC. 3,60,61 Recently, this approach has been criticized. Since reliable margin control is not achieved, the effectiveness of this treatment is highly dependent on the skill and experience of the physician.…”