Treatment of Scleroderma

Palmar fasciitis and polyarthritis syndrome associated with transitional cell carcinoma of the bladder

“…[47][48][49] Again, this does not seem to have resulted in a significant improvement in our patient. Another possible therapy is mycophenolate mofetil, which has been shown to have antifibrotic properties 50,51 in addition to its immunosuppressive actions.…”

Off-Label Dermatological Uses of Etanercept Treatment

“…Three of 4 patients with digital ulcers had clinical improvement of their lesions, while one had progressive disease. Pulmonary function tests, oral aperture, and hand extension measurements remained stable throughout the study [23]. There were no adverse events.…”

Combination Therapy for Psoriasis with Methotrexate and Other Oral Disease-Modifying Antirheumatic Drugs: A Systematic Review

“…0.59 2. 0.90 – – – – – – Lowenthal 2008 (United states) [ 30 ] Case series 18 MTX and acitretin Hb: 11.1% RBC: 11.1% WBC: 5.56% GGT: 22% (less than 2x normal) ALT: 11.1% Cr: 11.1% – – – – – Shivers 2019 (United states) [ 31 ] Case report 1 MTX and acitretin Hb remained low, similar to baseline (11.3–12.5 g/dL) – – – – – – – AbuHilal 2016 (Canada) [ 11 ] Retrospective cohort MTX and apremilast ( n = 15) – – – – Nausea and or vomiting: 20% Weight loss: 13% – – AST aspartate transaminase, Cr creatinine, CsA cyclosporine, DBP diastolic blood pressure, GFR glomerular filtration rate, GGT gamma-glutamyl transferase, Hb hemoglobin, LEF leflunomide, MTX methotrexate, PIIINP procollagen III N-terminal propeptide, PSA psoriatic arthritis, RBC red blood cell, SBP systolic blood pressure, SD standard deviation, ULN upper limit of normal, URI upper respiratory tract infection, UTI urinary tract infection, WBC white blood cell * United States, Canada, Australia, Belgium, France, Germany, Spain, United Kingdom, Czech Republic, Poland, Russian Federation, Slovakia, Brazil, Mexico, Taiwan, Bulgaria, Hungary † OPAL Broaden, NCT01877668; OPAL Beyond, NCT01882439 ...…”