“…In agreement with this hypothesis, mucin deposition is a common histopathological finding in LE, and another form of cutaneous mucinosis, the so-called papulonodular mucinosis, has also been associated with LE [6]. Similarly to LE, REM is successfully treated with hydroxychloroquine and chloroquine; however, other treatment regimens, including UVA1 radiation, topical tacrolimus and pulsed dye laser, have recently been reported to be effective with fewer side effects than antimalarial drugs [7,8,9]. …”