Treatment of Psoriasis with Long-Wave Ultraviolet Light

Young, E; Leun, Jan C. van der

doi:10.1159/000251456

Cited by 19 publications

(5 citation statements)

References 6 publications

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“…There may be concern that tanning beds that emit primarily UVA would not be effective for the treatment of psoriasis. While one study found that UVA doses up to 30 J/cm 2 were ineffective for psoriasis, Parrish [ 16 ] found that psoriatic plaques are responsive to erythemogenic doses of either UVA or UVB light [ 16 , 17 ]. The ability of tanning beds to treat psoriasis was compared on the basis of their UVB output, one with a UVB output of 4.6% was compared to another with a lower UVB output (0.7%) in a within-patient comparison technique [ 18 ].…”

Section: Resultsmentioning

confidence: 99%

A Review of the Use of Tanning Beds as a Dermatological Treatment

Radack

Farhangian

Anderson

et al. 2015

Dermatol Ther (Heidelb)

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IntroductionIn-office phototherapy is an effective treatment for many dermatologic conditions, however, many patients are unable to adhere to the rigorous travel and time commitments sometimes needed. Tanning bed facilities are nearly ubiquitous in modern society and could represent a more convenient means to obtain ultraviolet (UV) exposure when office phototherapy is not feasible. The purpose of this study was to review available evidence on the use of tanning facilities as a treatment for dermatologic conditions.MethodsPubMed was searched on February 2015 for “tanning beds” and “phototherapy”, and with some dermatologic conditions sensitive to UV light, including “psoriasis”, “mycosis fungoides”, “acne”, “atopic dermatitis” and “eczema”. From there, further articles were found using the reference sections of the initial papers. A similar methodology was used with the Google Scholar search engine. Only articles in English and prospective studies were included in this review.ResultsWe found studies validating the use of tanning facilities for psoriasis treatment. Use as a treatment option for atopic dermatitis, mycosis fungoides, acne, scleroderma, vitiligo, and pruritus, as well as other UV sensitive dermatoses, may also be beneficial. This study is limited by the lack of double-blind, placebo-controlled trials, long-term follow-up studies, and meta-analyses for tanning facility use in dermatologic phototherapy, and by the lack of standardization of both tanning facilities and exposure dosing.ConclusionUnsupervised sun exposure is a standard recommendation for some patients to obtain phototherapy. Selected use of commercial tanning beds in the treatment of dermatologic conditions may be another useful and effective treatment for those patients with an inability to access office-based or home-based phototherapy.Electronic supplementary materialThe online version of this article (doi:10.1007/s13555-015-0071-8) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

A Review of the Use of Tanning Beds as a Dermatological Treatment

Radack

Farhangian

Anderson

et al. 2015

Dermatol Ther (Heidelb)

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“…In studies comparing UVA and UVB use with coal tar, UVA contributed little compared with UVB (3). Studies using 7-14 J/cm 2 and up to 30 J/cm 2 doses of UVA concluded that UVA was not effective for psoriasis (4). The minimum erythema dose for UVA is between 10 and 100 J/cm 2 , so it is possible that these studies of UVA for psoriasis did not use a sufficient dose to observe efficacy (5).…”

Section: Resultsmentioning

confidence: 99%

The role of commercial tanning beds and ultraviolet A light in the treatment of psoriasis

Pearce

Feldman

2005

Journal of Dermatological Treatment

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Background: Phototherapy is an effective, safe psoriasis treatment administered via office-based units or home devices. There is controversy over the use of commercial tanning beds; ultraviolet B (UVB) has documented efficacy although commercial beds emit largely UVA. Objective: To determine the efficacy of UVA and the role of commercial tanning beds in treating psoriasis. Methods: A literature search of UVA and commercial tanning was performed. Results: UVA can be effective for psoriasis, but achieving the high doses required may not be practical. Tanning beds do emit UVB although amounts are variable. Because of variability in UVA and UVB output in different tanning bulbs, it is difficult to predict response rates using commercial tanning beds. Conclusions: UVA can be used to treat psoriasis but may not be practical. Commercial tanning beds, emitting both UVA and UVB, have a role in treating psoriasis as an alternative to office-based therapy.

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“…1976;Parrish 1977;Petrozzi 1978;Petrozzi et ul. 1978;Young and Van Der Leun 1975). The controversy about Tar urtd y hotcstherapy (Parrish 1978) still exists (Tanenbaum, Parrish et al 1975;.…”

Section: Introductionmentioning

confidence: 99%

The effects of coal tar and ultraviolet radiation upon the incorporation of thymidine into DNA by Ehrlich ascites carcinoma cells in vitro

Menon¹,

Haberman²

1980

Can. J. Physiol. Pharmacol.

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The effects of coal tar with and without radiation from three types of sources upon the incorporation of thymidine into DNA by Ehrlich ascites carcinoma cells were investigated. It was found that addition of varying concentrations of coal tar inhibited the thymidine incorporation by progressively greater amounts. Irradiation by mercury vapor lamp or fluorescent tubes, both emitting predominantly UVA (320-400 nm) and visible radiations, inhibited the DNA synthesis to a small extent. However irradiation with either of these sources in the presence of tar gave a synergistic effect on the DNA synthesis. Irradiation with a predominantly UVB (260--320nm) source inhibited the DNA synthesis to a large extent. Irradiation with this source in the presence of coal tar did not give a synergistic effect but gave a summation effect. These findings have relevance in helping to choose the approporate radiation source for tar phototherapy of psoriasis. This in vitro system could also be used for other applications such as determining potencies of various tars or tar fractions.

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Treatment of Psoriasis with Long-Wave Ultraviolet Light

Abstract: The effect of long-wave ultraviolet light on psoriasis was studied in 10 patients, using the method of paired comparisons. The radiation failed to have any demonstrable effect.

Cited by 19 publications

References 6 publications

A Review of the Use of Tanning Beds as a Dermatological Treatment

A Review of the Use of Tanning Beds as a Dermatological Treatment

The role of commercial tanning beds and ultraviolet A light in the treatment of psoriasis

The effects of coal tar and ultraviolet radiation upon the incorporation of thymidine into DNA by Ehrlich ascites carcinoma cells in vitro

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