“…The combination of rigid plate fixation and iliac crest autograft results in a high success rate for aseptic non-union of the humeral shaft when no large defects are present [3,4,9,12,15,17,18,20,21,32,[34][35][36]. The inherent biomechanics of the humeral shaft can explain why intramedullary (IM) nailing is not as successful as in the lower limb [1,2,7,13,19,28,34]. Persistent non-union can be defined as known failure of at least one surgical attempt at bone union in a confirmed case of nonunion.…”