Treatment of Laryngeal Carcinoma With Conservative Surgery and Postoperative Radiation Therapy

Lymph Node Metastases from Laryngeal and Pharyngeal Carcinomas: Calculation of Burden of Metastasis and its Impact on Prognosis

“…The presence of primary lymph node metastases in the neck is most frequent among patients with pharyngeal and supraglottic carcinomas (6,7,(18)(19)(20)(21). In our series, the 5-year survival rates of these two groups of patients are almost the same: 37% and 40%, respectively (Figs.…”

Improved diagnostic accuracy in laryngeal cancer using a new classification based on computed tomography

“…'-' ' Other researchers favor primary surgery and postoperative radiation. 6 The greater the accuracy of defining the superior and inferior limits of tumor as well as its deep extension preoperatively, the more reliable the studies will be that correlate treatment choice with prognosis. Since the quality of survival is also of great importance, an accurate definition of tumor boundaries preoperatively may make conservation surgery a reasonable alternative to total laryngectomy in selected patients.…”

Complications of Postoperative Radiation Therapy after Partial Laryngectomy in Supraglottic Cancer: A Long‐Term Evaluation

“…In an attempt to increase locoregional control and survival, PRT has been advocated for positive or close margins, thyroid cartilage invasion, tumor showing perineural extension or vascular invasion, multiple or bilateral positive lymph nodes, extracapsular spread of disease with or without invasion of the soft tissues of the neck, and prophylactic treatment of possible residual disease. 1,2 However, recent reports suggested that PRT after partial laryngectomy for supraglottic carcinoma did not decrease the locoregional recurrence rate or increase survival if a bilateral neck dissection was performed at the time of surgery and complete histologic evaluation ruled out multiple positive nodes and extracapsular spread of disease. [3][4][5][6][7][8] Various reports have documented the complications of PRT after partial laryngectomy in cancer of the supraglottis.…”