2021
DOI: 10.3389/fphar.2021.725126
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Treatment of Kawasaki Disease: A Network Meta-Analysis of Four Dosage Regimens of Aspirin Combined With Recommended Intravenous Immunoglobulin

Abstract: Aspirin was once believed to reduce the mortality of Kawasaki disease (KD) due to its effect on the thrombotic occlusion of coronary arteries. However, conflicting evidence has been found regarding aspirin treatment and its benefit in patients with acute KD. We compared the efficacy of different aspirin doses in acute KD. A literature search of PubMed, EMBASE, and Cochrane databases was conducted to identify studies comparing different doses of aspirin for acute KD. The primary outcome of interest was coronary… Show more

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Cited by 4 publications
(2 citation statements)
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“…132 Aspirin is routinely used for its anti-inflammatory and antiplatelet effects, but it does not reduce the incidence of coronary artery aneurysms. 150…”
Section: Congenital Cardiovascular Defects and Kawasaki Diseasementioning
confidence: 99%
“…132 Aspirin is routinely used for its anti-inflammatory and antiplatelet effects, but it does not reduce the incidence of coronary artery aneurysms. 150…”
Section: Congenital Cardiovascular Defects and Kawasaki Diseasementioning
confidence: 99%
“…159 Aspirin is routinely used for its anti-inflammatory and antiplatelet effects, but it does not reduce the incidence of coronary artery aneurysms. 178…”
Section: Congenital Cardiovascular Defects and Kawasaki Diseasementioning
confidence: 99%