Treatment of Dermatophytosis and Hyperhidrosis With Formaldehyde and Cupric Sulfate Iontophoresis

Freis, Edward D.

doi:10.1001/archderm.1946.01510300037008

Cited by 7 publications

(2 citation statements)

References 4 publications

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“…The principle o f tap water iontophoresis was first described by Japanese authors [12] and then adopted by physiotherapists [13] and dermatologists [14,15] in the United States of America. The elaborate experimental studies of Bouman and Grunewald-Lentzer [13] showed that the use of two separate trays was more effective than placing both elec trodes in one single vessel.…”

Section: Introductionmentioning

confidence: 99%

Long-Term Efficacy and Side Effects of Tap Water Iontophoresis of Palmoplantar Hyperhidrosis – the Usefulness of Home Therapy

Hölzle¹,

Alberti²

1987

Dermatology

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Treatment of palmoplantar hyperhidrosis was carried out with a conventional galvanic generator in 40 patients and with a newly developed iontophoresis apparatus, which is suited for home treatment, in 31 patients. The new apparatus is operated by a rechargeable energy source or by batteries and is disconnected from the electrical net during treatment. It conforms to most recent safety regulations as approved by Underwriter’s Laboratory. Hyperhidrosis was completely controlled after 10–12 treatments as revealed by quantitative gravimetric measurements of sweat rates and semiquantitative estimation of starch iodine paper imprints. There was no apparent difference in efficacy between the two apparatuses. Not only hyperhidrosis was abolished, but associated symptoms, such as lividity of palms or soles, acral hypothermia and edema of fingers or toes, also subsided. Skin temperature on palms rose from 29.7 ± 1.8 °C before treatment to 32.2 ± 1.4 °C thereafter. Maintenance treatment was continued on an average for 14 months, in 4 patients for more than 3 years. No loss of efficacy was found during that period. Side effects were minimal and depended upon amperage used. Only slight discomfort during treatment and mild short-lasted skin irritation were observed. Long-term side effects did not occur.

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Section: Introductionmentioning

confidence: 99%

Long-Term Efficacy and Side Effects of Tap Water Iontophoresis of Palmoplantar Hyperhidrosis – the Usefulness of Home Therapy

Hölzle¹,

Alberti²

1987

Dermatology

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“…Diese Behandlung geht zurück auf Ichihashi [14], der 1936 erstmals eine Schweißhemmung durch den Ionentransport durch die Haut mithilfe verschiedener Lösungen beschrieb. Eine ähnliche Wirkung konnte Freis 1946 durch die Iontophorese von Formaldehyd und Kupfersulfat lösung erzielen [4]. Bouman und GrunewaldLentzer [2] behandelten erstmals die Hyperhidrosis der Handflächen und Fuß-sohlen durch eine Leitungswasseriontophorese.…”

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Leitungswasseriontophorese

Hölzle

2012

Hautarzt

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Since 1968, tap water iontophoresis has been employed as the method of choice for treating palmoplantar hyperhidrosis. Special electrodes also allow treatment of axillary hyperhidrosis. Tap water iontophoresis also can extend symptom -free intervals in dyshidrotic palmar eczema. The mechanism action is most likely a functional disturbance of the secretory mechanism of eccrine acini. During the induction phase, treatments are carried out once daily. Current direction may be switched before each treatment or, even better, kept constant until one side, preferably the dominant hand on the anode, is sweating normally. Then polarity is switched until both hands are adequately treated. During the weekly maintenance therapy, current direction is switched before each treatment. The most comfortable means of iontophoretic treatment employs pulsed direct current of high frequency (5-10 kHz) which is better tolerated than continuous direct current and also suitable for children. Side effects are minimal and transient. Only slight skin irritation or sensations of discomfort may occur during treatment. Electric burns and shocks can be avoided by following routine precautions. Contraindications for tap water iontophoresis are metallic implants, such as cardiac pacemakers, or orthopaedic joint or bone implants, if they are within the electric circuit. Defects in the skin barrier, which can not be protected by petrolatum or insulating tape, also represent a temporary contraindication. Treatment in pregnancy is contraindicated, since experience is lacking.

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Iontophoresis

Hölzle¹

2018

Kanerva’s Occupational Dermatology

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Treatment of Dermatophytosis and Hyperhidrosis With Formaldehyde and Cupric Sulfate Iontophoresis

Cited by 7 publications

References 4 publications

Long-Term Efficacy and Side Effects of Tap Water Iontophoresis of Palmoplantar Hyperhidrosis – the Usefulness of Home Therapy

Long-Term Efficacy and Side Effects of Tap Water Iontophoresis of Palmoplantar Hyperhidrosis – the Usefulness of Home Therapy

Leitungswasseriontophorese

Iontophoresis

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