Arch Dermatol
 2000
DOI: 10.1001/archderm.136.4.557
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Treatment of Cutaneous Warts With Squaric Acid Dibutylester: A Decade of Experience

Giuseppe Micali1
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Cited by 33 publications

(28 citation statements)
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“…Immunotherapy using an allergic contact sensitizer such as DNCB, squaric acid dibutylester (SADBE), and DPCP is a pain-free treatment that has a relatively high efficacy (45%-88%) based on previous reports and, therefore, is considered an effective treatment method. [2][3][4][5][6][7][8][9][10] In our study, positive clinical responses for DPCP as monotherapy were 75.6%, which are quite similar to the results from previous reports. Most studies of DPCP monotherapy only included patients who had immunotherapy after the failure of conventional treatment.…”
Section: Discussionsupporting
confidence: 90%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Immunotherapy using an allergic contact sensitizer such as DNCB, squaric acid dibutylester (SADBE), and DPCP is a pain-free treatment that has a relatively high efficacy (45%-88%) based on previous reports and, therefore, is considered an effective treatment method. [2][3][4][5][6][7][8][9][10] In our study, positive clinical responses for DPCP as monotherapy were 75.6%, which are quite similar to the results from previous reports. Most studies of DPCP monotherapy only included patients who had immunotherapy after the failure of conventional treatment.…”
Section: Discussionsupporting
confidence: 90%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Our study noted concurrent skin diseases in patients, as they are occasionally cited as a reason for lack of treatment response. One study mentioned immunosuppression and atopic dermatitis as reasons for nonresponse . Even in our limited patient population, our study suggests no association between atopic dermatitis and response .…”
Section: Discussioncontrasting
confidence: 67%
“…In our study, 83% of the 44 who could be reached for follow‐up reported resolution of their warts. Overall, prior reports of SADBE wart treatment documented response rates ranging from 58% to 84% . The highest reported success rate with SADBE treatment included pretreatment of warts with 70% salicylic acid under occlusion for 2 days, with a resolution rate of 84%; a similar rate was seen in our limited patient population (40 of 48 patients) who were available for follow‐up .…”
Section: Discussionsupporting
confidence: 59%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The rate of resolution we obtained treating patients with SADBE was confirmed to be quite high as demonstrated by several uncontrolled studies in which it ranged from 58% to 86%. 7,13,14,16–18 At 52-week follow-up, no recurrences were recorded in any responder patients of either group. Overall, therapy with SADBE was safe and well tolerated.…”
Section: Discussionmentioning
confidence: 88%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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