Treatment of Clinically Diagnosed Laryngopharyngeal Reflux Disease

Abstract

The incidence of HP infection in patients with LPRD in our study was 57%. Triple therapy showed a higher cure rate in patients with HPSA-positive test results.

Laryngopharengeal Reflux in Gastroesophageal Reflux Disease: Does “Silent Laryngopharengeal Reflux” Really Exist?

“…This was higher than that recorded by previous studies i.e. 38 and 32.4 years [24] [25]. In this study, postnasal drip and throat clearing were the most prevalent symptoms (96% each).…”

Sensitivity, Specificity, and Predictive Values of Laryngopharyngeal Reflux Symptoms and Signs in Clinical Practice

“…The comparison of this observation with the literature is limited because most authors used the reflux finding score, 19,23 which considers only laryngeal findings. In the literature, most studies reported that posterior commissure hypertrophy (43%‐89%) and laryngeal erythema (44%‐79%) were the most prevalent findings in patients with suspected or confirmed LPR 1,20,22,24 . In this study, laryngeal signs such as posterior commissure hypertrophy or laryngeal erythema had a high but comparable SE than pharyngeal (tongue tonsil hypertrophy) or oral (anterior pillar erythema) findings.…”

“…In the literature, most studies reported that posterior commissure hypertrophy (43%-89%) and laryngeal erythema (44%-79%) were the most prevalent findings in patients with suspected or confirmed LPR. 1,20,22,24 In this study, laryngeal signs such as posterior commissure hypertrophy or laryngeal erythema had a high but comparable SE than pharyngeal (tongue tonsil hypertrophy) or oral (anterior pillar erythema) findings. In this study, the evaluation of findings was performed by 2 laryngologists exhibiting an adequate interclass coefficient, which is a strength regarding the overall low interrater reliability outcome in previous reflux studies using the reflux finding score.…”

Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion

“…The current study did not show a correlation between LPR disease and H pylori infection or presence, as discussed by many authors 12 …”